diff --git a/Tests/test_file_jpeg2k.py b/Tests/test_file_jpeg2k.py
index fbf72ae0518..8bb290bf31d 100644
--- a/Tests/test_file_jpeg2k.py
+++ b/Tests/test_file_jpeg2k.py
@@ -325,6 +325,18 @@ def test_cmyk() -> None:
         assert im.getpixel((0, 0)) == (185, 134, 0, 0)
 
 
+@pytest.mark.skipif(
+    not os.path.exists(EXTRA_DIR), reason="Extra image files not installed"
+)
+@skip_unless_feature_version("jpg_2000", "2.5.3")
+def test_cmyk_save() -> None:
+    with Image.open(f"{EXTRA_DIR}/issue205.jp2") as jp2:
+        assert jp2.mode == "CMYK"
+
+        im = roundtrip(jp2)
+        assert_image_equal(im, jp2)
+
+
 @pytest.mark.parametrize("ext", (".j2k", ".jp2"))
 def test_16bit_monochrome_has_correct_mode(ext: str) -> None:
     with Image.open("Tests/images/16bit.cropped" + ext) as im:
diff --git a/src/libImaging/Jpeg2KEncode.c b/src/libImaging/Jpeg2KEncode.c
index d30ccde603e..34d1a22949c 100644
--- a/src/libImaging/Jpeg2KEncode.c
+++ b/src/libImaging/Jpeg2KEncode.c
@@ -330,6 +330,13 @@ j2k_encode_entry(Imaging im, ImagingCodecState state) {
         components = 4;
         color_space = OPJ_CLRSPC_SRGB;
         pack = j2k_pack_rgba;
+#if ((OPJ_VERSION_MAJOR == 2 && OPJ_VERSION_MINOR == 5 && OPJ_VERSION_BUILD >= 3) || \
+     (OPJ_VERSION_MAJOR == 2 && OPJ_VERSION_MINOR > 5) || OPJ_VERSION_MAJOR > 2)
+    } else if (strcmp(im->mode, "CMYK") == 0) {
+        components = 4;
+        color_space = OPJ_CLRSPC_CMYK;
+        pack = j2k_pack_rgba;
+#endif
     } else {
         state->errcode = IMAGING_CODEC_BROKEN;
         state->state = J2K_STATE_FAILED;