diff --git a/typescript/index.d.ts b/typescript/index.d.ts
index 0c3a4c45..6784dfe5 100644
--- a/typescript/index.d.ts
+++ b/typescript/index.d.ts
@@ -8,7 +8,7 @@ type JSONString = string;
  * Represents a molecule object generated by RDKit.js
  * 
  * @remarks
- * JSMol's are created using the {@link RDKitModule.get_mol | RDKitModule.get_mol()} methods. 
+ * JSMols are created using the {@link RDKitModule.get_mol | RDKitModule.get_mol()} methods. 
  */
 export interface JSMol {
 
@@ -211,7 +211,9 @@ export interface JSMol {
     options: JSONString
   ): string;
 
-  /** Returns true if the molecule's structure is valid */
+  /**
+   * @deprecated Please check the get_mol return value for non-nullness instead
+   */
   is_valid(): boolean;
 
   /** Check is the molecule has any 2D coordinates generated */
@@ -369,6 +371,86 @@ export interface JSMol {
 }
 
 
+/**
+ * Represents a reaction object generated by RDKit.js
+ * 
+ * @remarks
+ * JSReactions are created using the {@link RDKitModule.get_rxn | RDKitModule.get_rxn()} methods. 
+ */
+export interface JSReaction {
+
+  /** Returns an SVG of the reaction */
+  get_svg(): string;
+
+  /**
+   * Returns an SVG of the reaction
+   * 
+   * @param width Width in pixels
+   * @param height Height in pixels
+   */
+  get_svg(width: number, height: number): string;
+
+  /**
+   * Returns an SVG of the reaction, with atoms highlighted
+   * 
+   * @param details A stringified JSON object containing any of the following options https://www.rdkitjs.com/#drawing-molecules-all-options
+   */
+  get_svg_with_highlights(details: string): string;
+
+  /**
+   * Draw the reaction to an HTML5 canvas
+   * 
+   * @param canvas canvas ID
+   * @param width width in pixels
+   * @param height height in pixels
+   */
+  draw_to_canvas(
+    canvas: HTMLCanvasElement,
+    width: number,
+    height: number
+  ): void;
+
+  /**
+   * Draw the reaction to an HTML5 canvas with an offset
+   * 
+   * @param canvas canvas ID
+   * @param offsetx offset X in pixels
+   * @param offsety offset Y in pixels
+   * @param width width in pixels
+   * @param height height in pixels
+   */
+  draw_to_canvas_with_offset(
+    canvas: HTMLCanvasElement,
+    offsetx: number,
+    offsety: number,
+    width: number,
+    height: number
+  ): void;
+
+  /**
+   * Draw the reaction to an HTML5 canvas, with atom highlights
+   * 
+   * @param canvas canvas ID
+   * @param details A stringified JSON object containing any of the following options https://www.rdkitjs.com/#drawing-molecules-all-options
+   */
+  draw_to_canvas_with_highlights(
+    canvas: HTMLCanvasElement,
+    details: string
+  ): void;
+
+  /** Delete C++ reaction objects manually from memory
+   * 
+   * See {@link https://emscripten.org/docs/porting/connecting_cpp_and_javascript/embind.html#memory-management | Emscripten docs} for more details
+   */
+  delete(): void;
+
+  /**
+   * @deprecated Please check the get_rxn return value for non-nullness instead
+   */
+  is_valid(): boolean
+}
+
+
 /** 
  * An object containing a collection of structures. Used for efficient substructure searching.
  * 
@@ -456,6 +538,12 @@ export interface SubstructLibrary {
   count_matches(q: JSMol, useChirality: boolean, numThreads: number): number;
 }
 
+export interface JSLog {
+  clear_buffer(): void;
+  get_buffer(): string;
+  delete(): void;
+}
+
 // constructor interfaces
 
 /** Returns a new SubstructLibrary instance */
@@ -531,6 +619,26 @@ export interface RDKitModule {
    * @param value
    */
   use_legacy_stereo_perception(value: boolean): void;
+
+  /**
+   * Set whether to allow non-tetrahedral chirality
+   * 
+   * @param value
+   */
+  allow_non_tetrahedral_chirality(value: boolean): boolean;
+
+  /**
+   * Create a reaction from a variety of input strings.
+   * This will return null if the input is invalid.
+   * @param input 
+   * @param details_json 
+   */
+  get_rxn(input: string, details_json?: string): JSReaction | null
+
+  enable_logging(): void;
+  disable_logging(): void;
+  set_log_capture(log_name: string): JSLog;
+  set_log_tee(log_name: string): JSLog;
 }
 
 type RDKitLoaderOptions = {