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DESCRIPTION
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DESCRIPTION
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Package: CIMICE
Type: Package
Title: CIMICE-R: (Markov) Chain Method to Inferr Cancer Evolution
Version: 1.3.1
Authors@R:
c(
person("Nicolò", "Rossi",
role=c("aut", "cre"), email="[email protected]",
comment = c("Lab. of Computational Biology and Bioinformatics, Department of Mathematics, Computer Science and Physics, University of Udine",ORCID = "0000-0002-6353-7396"))
)
Description:
CIMICE is a tool in the field of tumor phylogenetics and
its goal is to build a Markov Chain (called Cancer Progression Markov Chain,
CPMC) in order to model tumor subtypes evolution.
The input of CIMICE is a Mutational Matrix, so a boolean matrix representing
altered genes in a collection of samples. These samples are assumed to be
obtained with single-cell DNA analysis techniques and the tool is
specifically written to use the peculiarities of this data for the CMPC
construction.
License: Artistic-2.0
Encoding: UTF-8
Imports:
dplyr,
ggplot2,
glue,
tidyr,
igraph,
networkD3,
visNetwork,
ggcorrplot,
purrr,
ggraph,
stats,
utils,
maftools,
assertthat,
tidygraph,
expm,
Matrix
RoxygenNote: 7.1.2
VignetteBuilder: knitr
Suggests:
BiocStyle,
knitr,
rmarkdown,
testthat,
webshot
biocViews:
Software,
BiologicalQuestion,
NetworkInference,
ResearchField,
Phylogenetics,
StatisticalMethod,
GraphAndNetwork,
Technology,
SingleCell
BugReports: https://github.com/redsnic/CIMICE/issues
URL: https://github.com/redsnic/CIMICE
BiocType: Software