diff --git a/sdcm/nemesis.py b/sdcm/nemesis.py
index 786cf16fad..f697c30a82 100644
--- a/sdcm/nemesis.py
+++ b/sdcm/nemesis.py
@@ -2042,6 +2042,10 @@ def disrupt_truncate_large_partition(self):
         it's used to cover one improvement of compaction.
         The increase frequency of checking abortion is very useful for truncate.
         """
+        if (SkipPerIssues(issues="https://github.com/scylladb/scylladb/issues/20356",
+                          params=self.tester.params)
+                and self.tester.params.get("use_zero_nodes")):
+            raise UnsupportedNemesis("Unsupported nemesis due to scylladb/scylladb#20356")
         ks_name = 'ks_truncate_large_partition'
         table = 'test_table'
         stress_cmd = "scylla-bench -workload=sequential -mode=write -replication-factor=3 -partition-count=10 " + \
diff --git a/test-cases/longevity/longevity-multi-dc-rack-aware-with-znode-in-diff_dc.yaml b/test-cases/longevity/longevity-multi-dc-rack-aware-with-znode-in-diff_dc.yaml
new file mode 100644
index 0000000000..99007eadf2
--- /dev/null
+++ b/test-cases/longevity/longevity-multi-dc-rack-aware-with-znode-in-diff_dc.yaml
@@ -0,0 +1,25 @@
+test_duration: 800
+
+prepare_write_cmd:  ["cassandra-stress write cl=LOCAL_QUORUM n=20971520 -schema 'replication(strategy=NetworkTopologyStrategy,replication_factor=3,eu-northscylla_node_north=0) compaction(strategy=SizeTieredCompactionStrategy)' -port jmx=6868 -mode cql3 native -rate threads=80 -pop seq=1..20971520 -col 'n=FIXED(10) size=FIXED(512)' -log interval=5",
+                    ]
+
+stress_cmd: ["cassandra-stress write cl=LOCAL_QUORUM duration=720m -schema 'replication(strategy=NetworkTopologyStrategy,replication_factor=3,eu-northscylla_node_north=0) compaction(strategy=SizeTieredCompactionStrategy)' -port jmx=6868 -mode cql3 native -rate threads=40 -pop 'dist=uniform(1..20971520)' -col 'n=FIXED(10) size=FIXED(512)' -log interval=5 -errors retries=50",
+             "cassandra-stress read  cl=LOCAL_QUORUM duration=720m -schema 'replication(strategy=NetworkTopologyStrategy,replication_factor=3,eu-northscylla_node_north=0) compaction(strategy=SizeTieredCompactionStrategy)' -port jmx=6868 -mode cql3 native -rate threads=40 -pop 'dist=uniform(1..20971520)' -col 'n=FIXED(10) size=FIXED(512)' -log interval=5 -errors retries=50",
+             ]
+
+n_db_nodes: '4 4 0'
+n_loaders: '1 1'
+n_monitor_nodes: 1
+n_db_zero_token_nodes: '0 1 1'
+
+instance_type_db: 'i4i.4xlarge'
+zero_token_instance_type_db: 'i4i.large'
+use_zero_nodes: true
+
+nemesis_class_name: 'SisyphusMonkey'
+nemesis_interval: 10
+nemesis_filter_seeds: false
+
+round_robin: false
+
+user_prefix: 'multi-dc-rackaware-with-znode-dc'