From 5174a300402bfcdf8389d66deb65676a11445dfc Mon Sep 17 00:00:00 2001 From: Incognita Data Science Date: Tue, 28 Jan 2025 10:48:18 +0100 Subject: [PATCH] Added common intro para --- vignettes/intropkg.Rmd | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/vignettes/intropkg.Rmd b/vignettes/intropkg.Rmd index 52b9ead..2ac2922 100644 --- a/vignettes/intropkg.Rmd +++ b/vignettes/intropkg.Rmd @@ -24,7 +24,7 @@ library(SimTOST) ``` - +In the `SimTOST` R package, which is specifically designed for sample size estimation for bioequivalence studies, hypothesis testing is based on the Two One-Sided Tests (TOST) procedure. [@sozu_sample_2015] In TOST, the equivalence test is framed as a comparison between the the null hypothesis of ‘new product is worse by a clinically relevant quantity’ and the alternative hypothesis of ‘difference between products is too small to be clinically relevant’. # Hypotheses