diff --git a/src/hotspot/share/jvmci/jvmciCompilerToVM.cpp b/src/hotspot/share/jvmci/jvmciCompilerToVM.cpp
index af72322ff4bf2..5f1de1c9221ef 100644
--- a/src/hotspot/share/jvmci/jvmciCompilerToVM.cpp
+++ b/src/hotspot/share/jvmci/jvmciCompilerToVM.cpp
@@ -710,8 +710,9 @@ C2V_END
 
 C2V_VMENTRY_0(jlong, getJObjectValue, (JNIEnv* env, jobject, jobject constant_jobject))
     requireNotInHotSpot("getJObjectValue", JVMCI_CHECK_0);
-    if (!THREAD->has_last_Java_frame()) {
-        JVMCI_THROW_MSG_0(IllegalStateException, err_msg("Cannot call getJObjectValue without Java frame anchor"));
+    // Ensure that we are not using the top-most JNIHandleBlock, which is never released.
+    if (!THREAD->has_last_Java_frame() && THREAD->active_handles()->pop_frame_link() == nullptr) {
+        JVMCI_THROW_MSG_0(IllegalStateException, err_msg("Cannot call getJObjectValue without Java frame anchor or a pushed JNI handle block"));
     }
     JVMCIObject constant = JVMCIENV->wrap(constant_jobject);
     Handle constant_value = JVMCIENV->asConstant(constant, JVMCI_CHECK_0);