diff --git a/CHANGELOG.md b/CHANGELOG.md
index 3f961323b4..c8fb41204a 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -15,10 +15,13 @@
 * Python, Node: Added PTTL command ([#1036](https://github.com/aws/glide-for-redis/pull/1036), [#1082](https://github.com/aws/glide-for-redis/pull/1082))
 * Node: Added HVAL command ([#1022](https://github.com/aws/glide-for-redis/pull/1022))
 * Node: Added PERSIST command ([#1023](https://github.com/aws/glide-for-redis/pull/1023))
+* Core: Enabled Cluster Mode periodic checks by default ([#1089](https://github.com/aws/glide-for-redis/pull/1089))
 
 #### Features
 
 * Python: Allow chaining function calls on transaction. ([#987](https://github.com/aws/glide-for-redis/pull/987))
+* Python: Added Cluster Mode configuration for periodic checks interval ([#1089](https://github.com/aws/glide-for-redis/pull/1089))
+
 
 ## 0.2.0 (2024-02-11)
 
diff --git a/glide-core/src/client/mod.rs b/glide-core/src/client/mod.rs
index 2ad44da68a..138e352045 100644
--- a/glide-core/src/client/mod.rs
+++ b/glide-core/src/client/mod.rs
@@ -2,7 +2,7 @@
  * Copyright GLIDE-for-Redis Project Contributors - SPDX Identifier: Apache-2.0
  */
 use crate::connection_request::{
-    ConnectionRequest, NodeAddress, ProtocolVersion, ReadFrom, TlsMode,
+    connection_request, ConnectionRequest, NodeAddress, ProtocolVersion, ReadFrom, TlsMode,
 };
 use crate::scripts_container::get_script;
 use futures::FutureExt;
@@ -26,6 +26,7 @@ pub const HEARTBEAT_SLEEP_DURATION: Duration = Duration::from_secs(1);
 
 pub const DEFAULT_RESPONSE_TIMEOUT: Duration = Duration::from_millis(250);
 pub const DEFAULT_CONNECTION_ATTEMPT_TIMEOUT: Duration = Duration::from_millis(250);
+pub const DEFAULT_PERIODIC_CHECKS_INTERVAL: Duration = Duration::from_secs(60);
 pub const INTERNAL_CONNECTION_TIMEOUT: Duration = Duration::from_millis(250);
 
 pub(super) fn get_port(address: &NodeAddress) -> u16 {
@@ -284,11 +285,23 @@ async fn create_cluster_client(
         .collect();
     let read_from = request.read_from.enum_value().unwrap_or(ReadFrom::Primary);
     let read_from_replicas = !matches!(read_from, ReadFrom::Primary,); // TODO - implement different read from replica strategies.
+    let periodic_checks = match request.periodic_checks {
+        Some(periodic_checks) => match periodic_checks {
+            connection_request::Periodic_checks::PeriodicChecksManualInterval(interval) => {
+                Some(Duration::from_secs(interval.duration_in_sec.into()))
+            }
+            connection_request::Periodic_checks::PeriodicChecksDisabled(_) => None,
+        },
+        None => Some(DEFAULT_PERIODIC_CHECKS_INTERVAL),
+    };
     let mut builder = redis::cluster::ClusterClientBuilder::new(initial_nodes)
         .connection_timeout(INTERNAL_CONNECTION_TIMEOUT);
     if read_from_replicas {
         builder = builder.read_from_replicas();
     }
+    if let Some(interval_duration) = periodic_checks {
+        builder = builder.periodic_topology_checks(interval_duration);
+    }
     builder = builder.use_protocol(convert_to_redis_protocol(
         request.protocol.enum_value_or_default(),
     ));
@@ -388,7 +401,6 @@ fn sanitized_request_string(request: &ConnectionRequest) -> String {
     let connection_retry_strategy = request.connection_retry_strategy.0.as_ref().map(|strategy|
             format!("\nreconnect backoff strategy: number of increasing duration retries: {}, base: {}, factor: {}",
         strategy.number_of_retries, strategy.exponent_base, strategy.factor)).unwrap_or_default();
-
     let protocol = request
         .protocol
         .enum_value()
@@ -397,9 +409,30 @@ fn sanitized_request_string(request: &ConnectionRequest) -> String {
     let client_name = chars_to_string_option(&request.client_name)
         .map(|client_name| format!("\nClient name: {client_name}"))
         .unwrap_or_default();
+    let periodic_checks = if request.cluster_mode_enabled {
+        match request.periodic_checks {
+            Some(ref periodic_checks) => match periodic_checks {
+                connection_request::Periodic_checks::PeriodicChecksManualInterval(interval) => {
+                    format!(
+                        "\nPeriodic Checks: Enabled with manual interval of {:?}s",
+                        interval.duration_in_sec
+                    )
+                }
+                connection_request::Periodic_checks::PeriodicChecksDisabled(_) => {
+                    "\nPeriodic Checks: Disabled".to_string()
+                }
+            },
+            None => format!(
+                "\nPeriodic Checks: Enabled with default interval of {:?}",
+                DEFAULT_PERIODIC_CHECKS_INTERVAL
+            ),
+        }
+    } else {
+        "".to_string()
+    };
 
     format!(
-        "\nAddresses: {addresses}{tls_mode}{cluster_mode}{request_timeout}{rfr_strategy}{connection_retry_strategy}{database_id}{protocol}{client_name}",
+        "\nAddresses: {addresses}{tls_mode}{cluster_mode}{request_timeout}{rfr_strategy}{connection_retry_strategy}{database_id}{protocol}{client_name}{periodic_checks}",
     )
 }
 
diff --git a/glide-core/src/protobuf/connection_request.proto b/glide-core/src/protobuf/connection_request.proto
index 4745365ef9..ecdeeae1b2 100644
--- a/glide-core/src/protobuf/connection_request.proto
+++ b/glide-core/src/protobuf/connection_request.proto
@@ -29,6 +29,13 @@ enum ProtocolVersion {
     RESP2 = 1; 
 }
 
+message PeriodicChecksManualInterval {
+    uint32 duration_in_sec = 1;
+}
+
+message PeriodicChecksDisabled {
+}
+
 // IMPORTANT - if you add fields here, you probably need to add them also in client/mod.rs:`sanitized_request_string`.
 message ConnectionRequest {
     repeated NodeAddress addresses = 1;
@@ -41,6 +48,10 @@ message ConnectionRequest {
     uint32 database_id = 8;
     ProtocolVersion protocol = 9;
     string client_name = 10;
+    oneof periodic_checks {
+        PeriodicChecksManualInterval periodic_checks_manual_interval = 11;
+        PeriodicChecksDisabled periodic_checks_disabled = 12;
+    }
 }
 
 message ConnectionRetryStrategy {
diff --git a/python/python/glide/config.py b/python/python/glide/config.py
index 581d686608..1c5fa9bd90 100644
--- a/python/python/glide/config.py
+++ b/python/python/glide/config.py
@@ -1,7 +1,7 @@
 # Copyright GLIDE-for-Redis Project Contributors - SPDX Identifier: Apache-2.0
 
 from enum import Enum
-from typing import List, Optional
+from typing import List, Optional, Union
 
 from glide.protobuf.connection_request_pb2 import ConnectionRequest
 from glide.protobuf.connection_request_pb2 import ProtocolVersion as SentProtocolVersion
@@ -92,6 +92,33 @@ def __init__(
         self.username = username
 
 
+class PeriodicChecksManualInterval:
+    def __init__(self, duration_in_sec: int) -> None:
+        """
+        Represents a manually configured interval for periodic checks.
+
+        Args:
+            duration_in_sec (int): The duration in seconds for the interval between periodic checks.
+        """
+        self.duration_in_sec = duration_in_sec
+
+
+class PeriodicChecksStatus(Enum):
+    """
+    Represents the cluster's periodic checks status.
+    To configure specific interval, see PeriodicChecksManualInterval.
+    """
+
+    ENABLED_DEFAULT_INTERVAL = 0
+    """
+    Periodic checks are enabled with the default interval between checks.
+    """
+    DISABLED = 1
+    """
+    Periodic checks are disabled.
+    """
+
+
 class BaseClientConfiguration:
     def __init__(
         self,
@@ -191,7 +218,7 @@ class RedisClientConfiguration(BaseClientConfiguration):
         reconnect_strategy (Optional[BackoffStrategy]): Strategy used to determine how and when to reconnect, in case of
             connection failures.
             If not set, a default backoff strategy will be used.
-        database_id (Optional[Int]): index of the logical database to connect to.
+        database_id (Optional[int]): index of the logical database to connect to.
         client_name (Optional[str]): Client name to be used for the client. Will be used with CLIENT SETNAME command during connection establishment.
         protocol (ProtocolVersion): The version of the Redis RESP protocol to communicate with the server.
     """
@@ -224,7 +251,7 @@ def _create_a_protobuf_conn_request(
         self, cluster_mode: bool = False
     ) -> ConnectionRequest:
         assert cluster_mode is False
-        request = super()._create_a_protobuf_conn_request(False)
+        request = super()._create_a_protobuf_conn_request(cluster_mode)
         if self.reconnect_strategy:
             request.connection_retry_strategy.number_of_retries = (
                 self.reconnect_strategy.num_of_retries
@@ -259,6 +286,10 @@ class ClusterClientConfiguration(BaseClientConfiguration):
             If the specified timeout is exceeded for a pending request, it will result in a timeout error. If not set, a default value will be used.
         client_name (Optional[str]): Client name to be used for the client. Will be used with CLIENT SETNAME command during connection establishment.
         protocol (ProtocolVersion): The version of the Redis RESP protocol to communicate with the server.
+        periodic_checks (Union[PeriodicChecksStatus, PeriodicChecksManualInterval]): Configure the periodic topology checks.
+            These checks evaluate changes in the cluster's topology, triggering a slot refresh when detected.
+            Periodic checks ensure a quick and efficient process by querying a limited number of nodes.
+            Defaults to PeriodicChecksStatus.ENABLED_DEFAULT_INTERVAL.
 
     Notes:
         Currently, the reconnection strategy in cluster mode is not configurable, and exponential backoff
@@ -274,6 +305,9 @@ def __init__(
         request_timeout: Optional[int] = None,
         client_name: Optional[str] = None,
         protocol: ProtocolVersion = ProtocolVersion.RESP3,
+        periodic_checks: Union[
+            PeriodicChecksStatus, PeriodicChecksManualInterval
+        ] = PeriodicChecksStatus.ENABLED_DEFAULT_INTERVAL,
     ):
         super().__init__(
             addresses=addresses,
@@ -284,3 +318,18 @@ def __init__(
             client_name=client_name,
             protocol=protocol,
         )
+        self.periodic_checks = periodic_checks
+
+    def _create_a_protobuf_conn_request(
+        self, cluster_mode: bool = False
+    ) -> ConnectionRequest:
+        assert cluster_mode is True
+        request = super()._create_a_protobuf_conn_request(cluster_mode)
+        if type(self.periodic_checks) is PeriodicChecksManualInterval:
+            request.periodic_checks_manual_interval.duration_in_sec = (
+                self.periodic_checks.duration_in_sec
+            )
+        elif self.periodic_checks == PeriodicChecksStatus.DISABLED:
+            request.periodic_checks_disabled.SetInParent()
+
+        return request
diff --git a/python/python/tests/test_config.py b/python/python/tests/test_config.py
index 5bcada20c2..ccd4d82a77 100644
--- a/python/python/tests/test_config.py
+++ b/python/python/tests/test_config.py
@@ -1,6 +1,13 @@
 # Copyright GLIDE-for-Redis Project Contributors - SPDX Identifier: Apache-2.0
 
-from glide.config import BaseClientConfiguration, NodeAddress, ReadFrom
+from glide.config import (
+    BaseClientConfiguration,
+    ClusterClientConfiguration,
+    NodeAddress,
+    PeriodicChecksManualInterval,
+    PeriodicChecksStatus,
+    ReadFrom,
+)
 from glide.protobuf.connection_request_pb2 import ConnectionRequest
 from glide.protobuf.connection_request_pb2 import ReadFrom as ProtobufReadFrom
 from glide.protobuf.connection_request_pb2 import TlsMode
@@ -28,3 +35,20 @@ def test_convert_to_protobuf():
     assert request.tls_mode is TlsMode.SecureTls
     assert request.read_from == ProtobufReadFrom.PreferReplica
     assert request.client_name == "TEST_CLIENT_NAME"
+
+
+def test_periodic_checks_interval_to_protobuf():
+    config = ClusterClientConfiguration(
+        [NodeAddress("127.0.0.1")],
+    )
+    request = config._create_a_protobuf_conn_request(cluster_mode=True)
+    assert not request.HasField("periodic_checks_disabled")
+    assert not request.HasField("periodic_checks_manual_interval")
+
+    config.periodic_checks = PeriodicChecksStatus.DISABLED
+    request = config._create_a_protobuf_conn_request(cluster_mode=True)
+    assert request.HasField("periodic_checks_disabled")
+
+    config.periodic_checks = PeriodicChecksManualInterval(30)
+    request = config._create_a_protobuf_conn_request(cluster_mode=True)
+    assert request.periodic_checks_manual_interval.duration_in_sec == 30