diff --git a/go/vt/vtgate/evalengine/eval_result.go b/go/vt/vtgate/evalengine/eval_result.go
index d9916af03be..5c1973d8eb1 100644
--- a/go/vt/vtgate/evalengine/eval_result.go
+++ b/go/vt/vtgate/evalengine/eval_result.go
@@ -62,6 +62,7 @@ func (er EvalResult) String() string {
 
 // TupleValues allows for retrieval of the value we expose for public consumption
 func (er EvalResult) TupleValues() []sqltypes.Value {
+	// TODO: Make this collation-aware
 	switch v := er.v.(type) {
 	case *evalTuple:
 		result := make([]sqltypes.Value, 0, len(v.t))
diff --git a/go/vt/vttablet/tabletserver/vstreamer/planbuilder.go b/go/vt/vttablet/tabletserver/vstreamer/planbuilder.go
index 9bbc98ca2bd..96babb35666 100644
--- a/go/vt/vttablet/tabletserver/vstreamer/planbuilder.go
+++ b/go/vt/vttablet/tabletserver/vstreamer/planbuilder.go
@@ -89,6 +89,8 @@ const (
 	NotEqual
 	// IsNotNull is used to filter a column if it is NULL
 	IsNotNull
+	// In is used to filter a comparable column if equals any of the values from a specific tuple
+	In
 )
 
 // Filter contains opcodes for filtering.
@@ -97,6 +99,9 @@ type Filter struct {
 	ColNum int
 	Value  sqltypes.Value
 
+	// Values will be used to store tuple/list values.
+	Values []sqltypes.Value
+
 	// Parameters for VindexMatch.
 	// Vindex, VindexColumns and KeyRange, if set, will be used
 	// to filter the row.
@@ -166,6 +171,8 @@ func getOpcode(comparison *sqlparser.ComparisonExpr) (Opcode, error) {
 		opcode = GreaterThanEqual
 	case sqlparser.NotEqualOp:
 		opcode = NotEqual
+	case sqlparser.InOp:
+		opcode = In
 	default:
 		return -1, fmt.Errorf("comparison operator %s not supported", comparison.Operator.ToString())
 	}
@@ -238,6 +245,24 @@ func (plan *Plan) filter(values, result []sqltypes.Value, charsets []collations.
 			if values[filter.ColNum].IsNull() {
 				return false, nil
 			}
+		case In:
+			if filter.Values == nil {
+				return false, vterrors.Errorf(vtrpcpb.Code_INTERNAL, "unexpected empty filter values when performing IN operator")
+			}
+			found := false
+			for _, filterValue := range filter.Values {
+				match, err := compare(Equal, values[filter.ColNum], filterValue, plan.env.CollationEnv(), charsets[filter.ColNum])
+				if err != nil {
+					return false, err
+				}
+				if match {
+					found = true
+					break
+				}
+			}
+			if !found {
+				return false, nil
+			}
 		default:
 			match, err := compare(filter.Opcode, values[filter.ColNum], filter.Value, plan.env.CollationEnv(), charsets[filter.ColNum])
 			if err != nil {
@@ -514,6 +539,27 @@ func (plan *Plan) getColumnFuncExpr(columnName string) *sqlparser.FuncExpr {
 	return nil
 }
 
+func (plan *Plan) appendTupleFilter(values sqlparser.ValTuple, opcode Opcode, colnum int) error {
+	pv, err := evalengine.Translate(values, &evalengine.Config{
+		Collation:   plan.env.CollationEnv().DefaultConnectionCharset(),
+		Environment: plan.env,
+	})
+	if err != nil {
+		return err
+	}
+	env := evalengine.EmptyExpressionEnv(plan.env)
+	resolved, err := env.Evaluate(pv)
+	if err != nil {
+		return err
+	}
+	plan.Filters = append(plan.Filters, Filter{
+		Opcode: opcode,
+		ColNum: colnum,
+		Values: resolved.TupleValues(),
+	})
+	return nil
+}
+
 func (plan *Plan) analyzeWhere(vschema *localVSchema, where *sqlparser.Where) error {
 	if where == nil {
 		return nil
@@ -537,6 +583,13 @@ func (plan *Plan) analyzeWhere(vschema *localVSchema, where *sqlparser.Where) er
 			if err != nil {
 				return err
 			}
+			if opcode == In {
+				values, ok := expr.Right.(sqlparser.ValTuple)
+				if !ok {
+					return fmt.Errorf("unexpected: %v", sqlparser.String(expr))
+				}
+				return plan.appendTupleFilter(values, opcode, colnum)
+			}
 			val, ok := expr.Right.(*sqlparser.Literal)
 			if !ok {
 				return fmt.Errorf("unexpected: %v", sqlparser.String(expr))
diff --git a/go/vt/vttablet/tabletserver/vstreamer/planbuilder_test.go b/go/vt/vttablet/tabletserver/vstreamer/planbuilder_test.go
index ba345b2a00b..aba74368802 100644
--- a/go/vt/vttablet/tabletserver/vstreamer/planbuilder_test.go
+++ b/go/vt/vttablet/tabletserver/vstreamer/planbuilder_test.go
@@ -710,9 +710,15 @@ func TestPlanBuilderFilterComparison(t *testing.T) {
 		outFilters: []Filter{{Opcode: LessThan, ColNum: 0, Value: sqltypes.NewInt64(2)},
 			{Opcode: LessThanEqual, ColNum: 1, Value: sqltypes.NewVarChar("xyz")},
 		},
+	}, {
+		name:     "in-operator",
+		inFilter: "select * from t1 where id in (1, 2)",
+		outFilters: []Filter{
+			{Opcode: In, ColNum: 0, Values: []sqltypes.Value{sqltypes.NewInt64(1), sqltypes.NewInt64(2)}},
+		},
 	}, {
 		name:     "vindex-and-operators",
-		inFilter: "select * from t1 where in_keyrange(id, 'hash', '-80') and id = 2 and val <> 'xyz'",
+		inFilter: "select * from t1 where in_keyrange(id, 'hash', '-80') and id = 2 and val <> 'xyz' and id in (100, 30)",
 		outFilters: []Filter{
 			{
 				Opcode:        VindexMatch,
@@ -727,6 +733,7 @@ func TestPlanBuilderFilterComparison(t *testing.T) {
 			},
 			{Opcode: Equal, ColNum: 0, Value: sqltypes.NewInt64(2)},
 			{Opcode: NotEqual, ColNum: 1, Value: sqltypes.NewVarChar("xyz")},
+			{Opcode: In, ColNum: 0, Values: []sqltypes.Value{sqltypes.NewInt64(100), sqltypes.NewInt64(30)}},
 		},
 	}}