diff --git a/code/modules/organs/internal/brain.dm b/code/modules/organs/internal/brain.dm
index 37ad0b48af6..37ff68de533 100644
--- a/code/modules/organs/internal/brain.dm
+++ b/code/modules/organs/internal/brain.dm
@@ -20,7 +20,8 @@
 	var/mob/living/carbon/brain/brainmob = null
 	var/const/damage_threshold_count = 10
 	var/damage_threshold_value
-	var/healed_threshold = 1
+	// When TRUE - next Life() tick will trigger severe damage effects. Basically exists as a sort of a cooldown.
+	var/healed_threshold = TRUE
 	var/oxygen_reserve = 6
 
 /obj/item/organ/internal/brain/New(mob/living/carbon/holder)
@@ -44,14 +45,13 @@
 			handle_severe_brain_damage()
 
 		if(damage < (max_damage / 4))
-			healed_threshold = 1
+			healed_threshold = TRUE
 
 		handle_disabilities()
 		handle_damage_effects()
 
 		// Brain damage from low oxygenation or lack of blood.
 		if(owner.should_have_organ(BP_HEART))
-
 			// No heart? You are going to have a very bad time. Not 100% lethal because heart transplants should be a thing.
 			var/blood_volume = owner.get_blood_oxygenation()
 			if(blood_volume < BLOOD_VOLUME_SURVIVE)
@@ -61,51 +61,52 @@
 				oxygen_reserve = min(initial(oxygen_reserve), oxygen_reserve+1)
 			if(!oxygen_reserve) //(hardcrit)
 				owner.Paralyse(3)
-			var/can_heal = damage && damage < max_damage && (damage % damage_threshold_value || owner.chem_effects[CE_BRAIN_REGEN] || (!past_damage_threshold(3) && owner.chem_effects[CE_STABLE]))
+			var/can_heal = damage && damage < max_damage && (!past_damage_threshold(6) || owner.chem_effects[CE_BRAIN_REGEN])
 			var/damprob
 			//Effects of bloodloss
 			switch(blood_volume)
-
 				if(BLOOD_VOLUME_SAFE to INFINITY)
 					if(can_heal)
-						damage = max(damage-1, 0)
+						heal_damage(1)
 				if(BLOOD_VOLUME_OKAY to BLOOD_VOLUME_SAFE)
 					if(prob(1))
-						to_chat(owner, "<span class='warning'>You feel [pick("dizzy","woozy","faint")]...</span>")
-					damprob = owner.chem_effects[CE_STABLE] ? 30 : 60
+						to_chat(owner, SPAN_WARNING("You feel [pick("dizzy","woozy","faint")]..."))
+					damprob = owner.chem_effects[CE_STABLE] ? 15 : 60
 					if(!past_damage_threshold(2) && prob(damprob))
-						take_internal_damage(1)
+						take_internal_damage(0.25)
 				if(BLOOD_VOLUME_BAD to BLOOD_VOLUME_OKAY)
 					owner.eye_blurry = max(owner.eye_blurry,6)
-					damprob = owner.chem_effects[CE_STABLE] ? 40 : 80
+					damprob = owner.chem_effects[CE_STABLE] ? 20 : 80
 					if(!past_damage_threshold(4) && prob(damprob))
-						take_internal_damage(1)
+						take_internal_damage(0.5)
 					if(!owner.paralysis && prob(10))
 						owner.Paralyse(rand(1,3))
-						to_chat(owner, "<span class='warning'>You feel extremely [pick("dizzy","woozy","faint")]...</span>")
+						to_chat(owner, SPAN_WARNING("You feel extremely [pick("dizzy","woozy","faint")]..."))
 				if(BLOOD_VOLUME_SURVIVE to BLOOD_VOLUME_BAD)
 					owner.eye_blurry = max(owner.eye_blurry,6)
-					damprob = owner.chem_effects[CE_STABLE] ? 60 : 100
+					damprob = owner.chem_effects[CE_STABLE] ? 22 : 90
 					if(!past_damage_threshold(6) && prob(damprob))
 						take_internal_damage(1)
 					if(!owner.paralysis && prob(15))
 						owner.Paralyse(3,5)
-						to_chat(owner, "<span class='warning'>You feel extremely [pick("dizzy","woozy","faint")]...</span>")
+						to_chat(owner, SPAN_DANGER("You feel extremely [pick("dizzy","woozy","faint")]..."))
 				if(-(INFINITY) to BLOOD_VOLUME_SURVIVE) // Also see heart.dm, being below this point puts you into cardiac arrest.
 					owner.eye_blurry = max(owner.eye_blurry,6)
-					damprob = owner.chem_effects[CE_STABLE] ? 80 : 100
+					damprob = owner.chem_effects[CE_STABLE] ? 25 : 100
 					if(prob(damprob))
-						take_internal_damage(1)
-					if(prob(damprob))
-						take_internal_damage(1)
-	..()
+						take_internal_damage(2)
+		// Alkysine and the like passively heal brain damage below certain threshold
+		var/brain_heal_effect = owner.chem_effects[CE_BRAIN_REGEN]
+		if(brain_heal_effect && !past_damage_threshold(7 + brain_heal_effect))
+			heal_damage(brain_heal_effect)
+	return ..()
 
 /obj/item/organ/internal/brain/examine(mob/user)
 	. = ..()
 	if(brainmob && brainmob.client)//if thar be a brain inside... the brain.
-		to_chat(user, "You can feel the small spark of life still left in this one.")
+		to_chat(user, SPAN_NOTICE(SPAN_BOLD("You can feel the small spark of life still left in this one.")))
 	else
-		to_chat(user, "This one seems particularly lifeless. Perhaps it will regain some of its luster later..")
+		to_chat(user, SPAN_DEADSAY("This one seems particularly lifeless. Perhaps it will regain some of its luster later.."))
 
 /obj/item/organ/internal/brain/removed(mob/living/user)
 	if(!istype(owner))
@@ -139,7 +140,7 @@
 /obj/item/organ/internal/brain/surgical_fix(mob/user)
 	var/blood_volume = owner.get_blood_oxygenation()
 	if(blood_volume < BLOOD_VOLUME_SURVIVE)
-		to_chat(user, "<span class='danger'>Parts of [src] didn't survive the procedure due to lack of air supply!</span>")
+		to_chat(user, SPAN_DANGER("Parts of [src] didn't survive the procedure due to lack of air supply!"))
 		set_max_damage(Floor(max_damage - 0.25*damage))
 	heal_damage(damage)
 
@@ -196,7 +197,7 @@
 	if(H.mind)
 		H.mind.transfer_to(brainmob)
 
-	to_chat(brainmob, "<span class='notice'>You feel slightly disoriented. That's normal when you're just \a [initial(src.name)].</span>")
+	to_chat(brainmob, SPAN_NOTICE("You feel slightly disoriented. That's normal when you're just \a [initial(src.name)]."))
 	callHook("debrain", list(brainmob))
 
 /obj/item/organ/internal/brain/proc/get_current_damage_threshold()
@@ -207,7 +208,7 @@
 
 /obj/item/organ/internal/brain/proc/handle_severe_brain_damage()
 	set waitfor = FALSE
-	healed_threshold = 0
+	healed_threshold = FALSE
 	to_chat(owner, "<span class = 'notice' font size='10'><B>Where am I...?</B></span>")
 	sleep(5 SECONDS)
 	if(!owner)
@@ -244,17 +245,17 @@
 /obj/item/organ/internal/brain/proc/handle_damage_effects()
 	if(owner.stat)
 		return
-	if(damage > 0 && prob(1))
+	if(damage > 5 && prob(1))
 		owner.custom_pain("Your head feels numb and painful.",10)
 	if(is_bruised() && prob(1) && owner.eye_blurry <= 0)
-		to_chat(owner, "<span class='warning'>It becomes hard to see for some reason.</span>")
+		to_chat(owner, SPAN_WARNING("It becomes hard to see for some reason."))
 		owner.eye_blurry = 5
-	if(damage >= 0.5*max_damage && prob(1) && owner.get_active_hand())
-		to_chat(owner, "<span class='danger'>Your hand won't respond properly, and you drop what you are holding!</span>")
+	if(damage >= 0.5 * max_damage && prob(1) && owner.get_active_hand())
+		to_chat(owner, SPAN_DANGER("Your hand won't respond properly, and you drop what you are holding!"))
 		owner.unequip_item()
-	if(damage >= 0.6*max_damage)
+	if(damage >= 0.75 * max_damage)
 		owner.slurring = max(owner.slurring, 2)
 	if(is_broken())
 		if(!owner.lying)
-			to_chat(owner, "<span class='danger'>You black out!</span>")
+			to_chat(owner, SPAN_DANGER("You black out!"))
 		owner.Paralyse(10)