Investigating the effect of recombination on the rate of emergence of multi-drug resistance under different treatment strategies in Malaria.
A stochastic, agent-based model, built in C++. Complete description of model architecture
Includes python scripts for simple inference and visualizations in data/plotting/
.
mkdir build
cd build
cmake -S ../src -B .
make
./MalariaPopSim
- In
fitness_values.csv
: Adjust fitness of wildtype clones according to assumed length of transmission cycle - In
simulator.cpp
: starting clones and starting clone frequencies - In
settings.h
: everything else (demography, genetics map, recombination, treatment)