diff --git a/space2stats_api/src/space2stats/app.py b/space2stats_api/src/space2stats/app.py
index 50b34ed..6747e70 100644
--- a/space2stats_api/src/space2stats/app.py
+++ b/space2stats_api/src/space2stats/app.py
@@ -10,6 +10,7 @@
 from starlette_cramjam.middleware import CompressionMiddleware
 
 from .db import close_db_connection, connect_to_db
+from .errors import add_exception_handlers
 from .main import (
     SummaryRequest,
     get_available_fields,
@@ -22,11 +23,8 @@
 
 @asynccontextmanager
 async def lifespan(app: FastAPI):
-    """FastAPI Lifespan."""
-    # Create Connection Pool
     await connect_to_db(app)
     yield
-    # Close the Connection Pool
     await close_db_connection(app)
 
 
@@ -49,6 +47,8 @@ async def lifespan(app: FastAPI):
     s3_client=s3_client,
 )
 
+add_exception_handlers(app)
+
 
 @app.post("/summary", response_model=List[Dict[str, Any]])
 def get_summary(request: Request, body: SummaryRequest):
diff --git a/space2stats_api/src/space2stats/errors.py b/space2stats_api/src/space2stats/errors.py
new file mode 100644
index 0000000..9dc4c65
--- /dev/null
+++ b/space2stats_api/src/space2stats/errors.py
@@ -0,0 +1,46 @@
+from fastapi import HTTPException, Request
+from fastapi.exceptions import RequestValidationError
+from fastapi.responses import JSONResponse
+from psycopg import OperationalError
+
+
+async def database_exception_handler(request: Request, exc: OperationalError):
+    return JSONResponse(
+        status_code=500,
+        content={"error": "Database connection failed", "detail": str(exc)},
+    )
+
+
+async def http_exception_handler(request: Request, exc: HTTPException):
+    return JSONResponse(
+        status_code=exc.status_code,
+        content={"error": exc.detail},
+    )
+
+
+# Custom handler for validation errors (422 Unprocessable Entity)
+async def validation_exception_handler(request: Request, exc: RequestValidationError):
+    errors = exc.errors()
+    detailed_errors = [
+        {
+            "field": "->".join(map(str, err.get("loc", []))),
+            "message": err.get("msg"),
+            "type": err.get("type", "Unknown error type"),
+        }
+        for err in errors
+    ]
+
+    return JSONResponse(
+        status_code=422,
+        content={
+            "error": "Validation Error",
+            "details": detailed_errors,
+            "hint": "Check if 'fields' is a valid list and all provided fields exist.",
+        },
+    )
+
+
+def add_exception_handlers(app):
+    app.add_exception_handler(OperationalError, database_exception_handler)
+    app.add_exception_handler(HTTPException, http_exception_handler)
+    app.add_exception_handler(RequestValidationError, validation_exception_handler)
diff --git a/space2stats_api/src/tests/test_errors.py b/space2stats_api/src/tests/test_errors.py
new file mode 100644
index 0000000..94954f3
--- /dev/null
+++ b/space2stats_api/src/tests/test_errors.py
@@ -0,0 +1,71 @@
+import asyncio
+import json
+
+from fastapi import HTTPException
+from fastapi.exceptions import RequestValidationError
+from fastapi.testclient import TestClient
+from psycopg.errors import OperationalError
+
+from src.space2stats.app import app
+from src.space2stats.errors import (
+    database_exception_handler,
+    http_exception_handler,
+    validation_exception_handler,
+)
+
+client = TestClient(app)
+
+
+def test_database_exception_handler():
+    request = None
+    exception = OperationalError("Database connection failed")
+    response = asyncio.run(database_exception_handler(request, exception))
+
+    assert response.status_code == 500
+    response_data = json.loads(response.body.decode("utf-8"))
+    assert response_data == {
+        "error": "Database connection failed",
+        "detail": "Database connection failed",
+    }
+
+
+def test_http_exception_handler():
+    request = None
+    exception = HTTPException(status_code=404, detail="Not found")
+    response = asyncio.run(http_exception_handler(request, exception))
+
+    assert response.status_code == 404
+    response_data = json.loads(response.body.decode("utf-8"))
+    assert response_data == {
+        "error": "Not found",
+    }
+
+
+def test_validation_exception_handler():
+    request = None
+    exc = RequestValidationError(
+        [
+            {
+                "loc": ("body", "fields"),
+                "msg": "Input should be a valid list",
+                "type": "type_error.list",
+            }
+        ]
+    )
+    response = asyncio.run(validation_exception_handler(request, exc))
+
+    expected_response = {
+        "error": "Validation Error",
+        "details": [
+            {
+                "field": "body->fields",
+                "message": "Input should be a valid list",
+                "type": "type_error.list",
+            }
+        ],
+        "hint": "Check if 'fields' is a valid list and all provided fields exist.",
+    }
+
+    assert response.status_code == 422
+    response_data = json.loads(response.body.decode("utf-8"))
+    assert response_data == expected_response