diff --git a/openpype/hosts/blender/hooks/pre_add_python_use_system_env.py b/openpype/hosts/blender/hooks/pre_add_python_use_system_env.py
new file mode 100644
index 00000000000..08bf18b27bf
--- /dev/null
+++ b/openpype/hosts/blender/hooks/pre_add_python_use_system_env.py
@@ -0,0 +1,34 @@
+from openpype.lib.applications import PreLaunchHook, LaunchTypes
+
+
+class AddPythonUseSystemEnvArg(PreLaunchHook):
+    """Add `--python-use-system-env` arg to blender launch."""
+
+    # Append before file argument from add last workfile (at order 10)
+    order = 5
+    app_groups = {"blender"}
+    launch_types = {LaunchTypes.local}
+
+    def execute(self):
+
+        add_var = self.get_application_setting("add_python_use_system_env",
+                                               default=True)
+        if not add_var:
+            return
+
+        arg = "--python-use-system-env"
+        if arg not in self.launch_context.launch_args:
+            self.log.debug(f"Adding required {arg} argument")
+            self.launch_context.launch_args.append(arg)
+        else:
+            self.log.debug(f"Required {arg} argument already provided before "
+                           f"this prelaunch hook.")
+
+    def get_application_setting(self, key, default=None):
+        app = self.launch_context.application
+        group_name = app.group.name
+        app_name = app.name
+        return (
+            self.data["system_settings"]["applications"][group_name]
+                     ["variants"][app_name].get(key, default)
+        )
diff --git a/openpype/settings/defaults/system_settings/applications.json b/openpype/settings/defaults/system_settings/applications.json
index a5283751e97..9f2c0a31680 100644
--- a/openpype/settings/defaults/system_settings/applications.json
+++ b/openpype/settings/defaults/system_settings/applications.json
@@ -1204,17 +1204,12 @@
                     "linux": []
                 },
                 "arguments": {
-                    "windows": [
-                        "--python-use-system-env"
-                    ],
-                    "darwin": [
-                        "--python-use-system-env"
-                    ],
-                    "linux": [
-                        "--python-use-system-env"
-                    ]
+                    "windows": [],
+                    "darwin": [],
+                    "linux": []
                 },
-                "environment": {}
+                "environment": {},
+                "add_python_use_system_env": true
             },
             "2-90": {
                 "executables": {
@@ -1225,17 +1220,12 @@
                     "linux": []
                 },
                 "arguments": {
-                    "windows": [
-                        "--python-use-system-env"
-                    ],
-                    "darwin": [
-                        "--python-use-system-env"
-                    ],
-                    "linux": [
-                        "--python-use-system-env"
-                    ]
+                    "windows": [],
+                    "darwin": [],
+                    "linux": []
                 },
-                "environment": {}
+                "environment": {},
+                "add_python_use_system_env": true
             },
             "2-91": {
                 "executables": {
@@ -1246,17 +1236,12 @@
                     "linux": []
                 },
                 "arguments": {
-                    "windows": [
-                        "--python-use-system-env"
-                    ],
-                    "darwin": [
-                        "--python-use-system-env"
-                    ],
-                    "linux": [
-                        "--python-use-system-env"
-                    ]
+                    "windows": [],
+                    "darwin": [],
+                    "linux": []
                 },
-                "environment": {}
+                "environment": {},
+                "add_python_use_system_env": true
             },
             "__dynamic_keys_labels__": {
                 "2-83": "2.83",
@@ -1584,8 +1569,8 @@
                 "environment": {}
             },
             "__dynamic_keys_labels__": {
-                "5-1": "Unreal 5.1",
-                "5-0": "Unreal 5.0"
+                "5-0": "Unreal 5.0",
+                "5-1": "Unreal 5.1"
             }
         }
     },
diff --git a/openpype/settings/entities/schemas/system_schema/host_settings/schema_blender.json b/openpype/settings/entities/schemas/system_schema/host_settings/schema_blender.json
index 27ead6e6da1..7a27f40343c 100644
--- a/openpype/settings/entities/schemas/system_schema/host_settings/schema_blender.json
+++ b/openpype/settings/entities/schemas/system_schema/host_settings/schema_blender.json
@@ -32,6 +32,11 @@
                         "type": "schema_template",
                         "name": "template_host_variant_items",
                         "skip_paths": ["use_python_2"]
+                    },
+                    {
+                        "type": "boolean",
+                        "key": "add_python_use_system_env",
+                        "label": "Use --python-use-system-env argument"
                     }
                 ]
             }