Collection of pharmacodynamic response models, including concentration-response, inhibitor-response, and various receptor-response models that can be used for empirical fitting of response data.
General response functions:
- Concentration-Response
- Dose-Response
- Inhibitor-Response
Receptor occupation:
- Hill-Langmuir equation
Receptor-response functions:
- Hill equation
- Clark equation
- Operational model by Black and Leff
- Del Castillo-Katz model
- Three-parameter two-state model by Buchwald
- Gaddum equation (competitive antagonist model)
- noncompetitive antagonist model (Emax reduction)
Other response functions:
- CNiFERs-Response
Installs as the pharmacodynamic package.
You can install the package using pip sourced from the GitHub repo:
pip install https://github.com/Borealis-BioModeling/pharmacodynamic-response-models/archive/refs/tags/v0.2.0.zip
This project is licensed under the MIT License - see the LICENSE file for details
Please open a GitHub Issue.
If this package is useful in your research, please cite this GitHub repo: https://github.com/Borealis-BioModeling/pharmacodynamic-response-models