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DESCRIPTION
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DESCRIPTION
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Package: corral
Title: Correspondence Analysis for Single Cell Data
Version: 1.9.1
Date: 2023-02-09
Authors@R:
c(person(given = "Lauren", family = "Hsu",
role = c("aut", "cre"),
email = "[email protected]",
comment = c(ORCID = "0000-0002-6035-7381")),
person(given = "Aedin", family = "Culhane",
role = c("aut"),
email = "[email protected]",
comment = c(ORCID = "0000-0002-1395-9734")))
Description:
Correspondence analysis (CA) is a matrix factorization method, and is
similar to principal components analysis (PCA). Whereas PCA is designed for
application to continuous, approximately normally distributed data, CA is
appropriate for non-negative, count-based data that are in the same additive scale.
The corral package implements CA for dimensionality reduction of a single matrix of
single-cell data, as well as a multi-table adaptation of CA that leverages
data-optimized scaling to align data generated from different sequencing platforms
by projecting into a shared latent space. corral utilizes sparse matrices and a
fast implementation of SVD, and can be called directly on Bioconductor objects
(e.g., SingleCellExperiment) for easy pipeline integration.
The package also includes additional options, including variations of CA to
address overdispersion in count data (e.g., Freeman-Tukey chi-squared residual),
as well as the option to apply CA-style processing to continuous data
(e.g., proteomic TOF intensities) with the Hellinger distance adaptation of CA.
Imports:
ggplot2,
ggthemes,
grDevices,
gridExtra,
irlba,
Matrix,
methods,
MultiAssayExperiment,
pals,
reshape2,
SingleCellExperiment,
SummarizedExperiment,
transport
Suggests:
ade4,
BiocStyle,
CellBench,
DuoClustering2018,
knitr,
rmarkdown,
scater,
testthat
License: GPL-2
RoxygenNote: 7.1.2
VignetteBuilder: knitr
biocViews:
BatchEffect,
DimensionReduction,
GeneExpression,
Preprocessing,
PrincipalComponent,
Sequencing,
SingleCell,
Software,
Visualization
Encoding: UTF-8