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SantiagoSanchezF authored Feb 4, 2025
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* InterProScan > 5.52-86.0:
- https://interproscan-docs.readthedocs.io/en/latest/InstallationRequirements.html
Non Linux OS can't run InterProScan. InterProScan output must be provided in TSV or GFF3 format sing "--ip-file" and a GBK as SEQUENCE
* Bioconda: https://bioconda.github.io/user/install.html
* Bioconda: https://bioconda.github.io

#### Installation

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### antiSMASH compatibility

SanntiS prioritises seamless integration with various downstream analysis tools, leveraging a GFF3 file output for broad compatibility. In addition, one of the key features in this regard is the ability to generate an output compatible with [antiSMASH](https://docs.antismash.secondarymetabolites.org/sideloading/), a widely used tool in the BGC analysis ecosystem.
SanntiS prioritises seamless integration with various downstream analysis tools, leveraging a GFF3 file output for broad compatibility. In addition, one of the key features in this regard is the ability to generate an output compatible with [antiSMASH](https://doi.org/10.1093/nar/gkad344), a widely used tool in the BGC analysis ecosystem.

#### `--antismash_output` Option

SanntiS has an `--antismash_output` option. This option allows you to create a JSON file formatted according to the specifications of [antiSMASH v6](https://docs.antismash.secondarymetabolites.org/sideloading/).
SanntiS has an `--antismash_output` option. This option allows you to create a JSON file formatted according to the specifications of [antiSMASH](https://docs.antismash.secondarymetabolites.org/sideloading/).

```bash
sanntis --antismash_output True test/files/BGC0001472.fna
```
Executing the command above produces a file named with the suffix `antismash.json` facilitating its use in antiSMASH for enriched analysis. Specifically, this file can be uploaded to the [antiSMASH web server](https://antismash.secondarymetabolites.org) under 'Data input' > 'Upload extra annotations', allowing for an integrated analytical approach that leverages external annotation data.

## Cite
If you use SanntiS make sure to cite the publication
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