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skim0119 committed Dec 25, 2023
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2 changes: 1 addition & 1 deletion docs/MEA/design_files.md
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# Design Files for MEA

Design files of a variety of MEAs with different resolutions and configurations are provided here. Designs are made in GDS format using free software Klayout (https://www.klayout.de).
Design files of a variety of MEAs with different resolutions and configurations are provided here. Designs are made in GDS format using free software [Klayout](https://www.klayout.de).

## 59 electrode

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2 changes: 1 addition & 1 deletion docs/PCB/design_files.md
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# Design Files for PCB

The PCB design for each recording configuration is provided here. Designs are made using free software KiCad (https://www.kicad.org).
The PCB design for each recording configuration is provided here. Designs are made using free software [KiCad](https://www.kicad.org).

- [59 channel](PCB59.zip)
- This layout is compatible with the widely employed Multichannel Systems 60MEA series MEAs.
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2 changes: 1 addition & 1 deletion docs/Platform/design_files.md
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# Design Files

A list of materials and parts used to construct the recording platform can be found [here ](List_Materials.xlsx).
A list of materials and parts used to construct the recording platform can be found [here.](List_Materials.xlsx).

Design files (SOLIDWORKS) for each version of the hardware are provided below:

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2 changes: 1 addition & 1 deletion docs/Platform/hardware_design.md
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Upon loading a chip, the top layer is closed and locked with the pins gently making contact with metal pads patterned on the perimeter of the MEA. These pads, and the electronic tracks emanating from them, are designed to connect one-to-one with micro-electrodes located at the center of the chip, where neural substrates are plated and incubated. Signals sampled at each electrode are then transferred through these tracks, pogo pins and PCB before being received and processed by amplifier headstages located on the rear edge of the PCB. Intan Technologies headstages, connected to Open Ephys terminals through serial peripheral interface (SPI) cables, are utilized here because of their wide compatibility.

The platform is also designed with versatility that supports a range of recording capacitiesand configurations. Being compatible with a series of swappable PCB options, the platform can be configured with different recording capacities of 59, 128, 256 and 512 channels. Moreover, a series of add-on modules such as electrical and optical stimulators, fluidic interfaces and temperature sensors can be seamlessly integrated with the system for multimodal neuron stimulation and media refreshment. Made of fully customizable design and inexpensive materials, the hardware configuration is also easily reconfigurable to comply with industrial standard dimensions, such as the SBS 96-well micro-plate. This allows our system to be deployed inside common microscopic chambers, enabling concurrent imaging and electrophysiology recording.
The platform is also designed with versatility that supports a range of recording capacitiesand configurations. Being compatible with a series of swappable PCB options, the platform can be configured with different recording capacities of 59, 128, 256 and 512 channels. Moreover, a series of add-on modules such as electrical and optical stimulators, fluidic interfaces and temperature sensors can be seamlessly integrated with the system for multimodal neuron stimulation and media refreshment. Made of fully customizable design and inexpensive materials, the hardware configuration is also easily reconfigurable to comply with industrial standard dimensions, such as the SBS 96-well micro-plate. This allows our system to be deployed inside common microscopic chambers, enabling concurrent imaging and electrophysiology recording.
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