Updated synaptic modulation

Hjorthmedh · Jul 29, 2024 · 015a8ac · 015a8ac
1 parent efd4667
commit 015a8ac
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Showing 5 changed files with 501 additions and 82 deletions.
diff --git a/examples/notebooks/neuromodulation/data/connectivity.json b/examples/notebooks/neuromodulation/data/connectivity.json
@@ -2,8 +2,28 @@
     "regions": {
         "Cube": {
 	    "connectivity": {
-		"neuron,neuron": {
-		    "DA": {
+		"dspn,dspn": {
+		    "fake_glutamate": {
+			"conductance": [
+			    1e-9,
+			    1e-3
+			],
+			"channel_parameters": {
+			    "mod_file": "tmGlut",
+			    "parameter_file": "data/tmglut_DA_parameters.json"
+			},
+			"cluster_size": 1,
+			"cluster_spread": null,
+			"pruning": {
+			    "f1": null,
+			    "soft_max": null,
+			    "mu2": null,
+			    "a3": null,
+			    "cluster_pruning": false
+			}
+		    },
+
+		    "!DA": {
 			"conductance": [
 			    1e-9,
 			    1e-3

diff --git a/examples/notebooks/neuromodulation/data/tmglut_DA_parameters.json b/examples/notebooks/neuromodulation/data/tmglut_DA_parameters.json
@@ -0,0 +1,39 @@
+{
+    "low": {
+	"synapse": {
+	    "mod_pka_g_ampa_min": 1,
+	    "mod_pka_g_ampa_max": 1,
+	    "mod_pka_g_ampa_half": 12.5,
+	    "mod_pka_g_ampa_slope": 1,
+	    "mod_pka_g_nmda_min": 1,
+	    "mod_pka_g_nmda_max": 1.2,
+	    "mod_pka_g_nmda_half": 12.5,
+	    "mod_pka_g_nmda_slope": 1
+	}
+    },
+    "mid": {
+	"synapse": {
+	    "mod_pka_g_ampa_min": 1,
+	    "mod_pka_g_ampa_max": 1.15,
+	    "mod_pka_g_ampa_half": 12.5,
+	    "mod_pka_g_ampa_slope": 1,
+	    "mod_pka_g_nmda_min": 1,
+	    "mod_pka_g_nmda_max": 1.3,
+	    "mod_pka_g_nmda_half": 12.5,
+	    "mod_pka_g_nmda_slope": 1
+	}
+    },
+    "high": {
+	"synapse": {
+	    "mod_pka_g_ampa_min": 1,
+	    "mod_pka_g_ampa_max": 1.3,
+	    "mod_pka_g_ampa_half": 12.5,
+	    "mod_pka_g_ampa_slope": 1,
+	    "mod_pka_g_nmda_min": 1,
+	    "mod_pka_g_nmda_max": 1.6,
+	    "mod_pka_g_nmda_half": 12.5,
+	    "mod_pka_g_nmda_slope": 1
+	}
+    }
+
+}