_2024_Daffern_GMMA_PYR1

Scripts and output from "GMMA can stabilize proteins across different functional constraints"

by Nicolas Daffern, Kristoffer E. Johansson, Zachary T. Baumer, Nicholas R. Robertson, Janty Woojuh, Matthew A. Bedewitz, Zoë Davis, Ian Wheeldon, Sean Cutler, Kresten Lindorff-Larsen and Timothy A. Whitehead.

Contents

• sequencing_counts: Sequencing counts from screens
• enrichment: Script for calculating enrichment scores of all data sets
• gmma: Scripts for GMMA, subfolders contain a run.sh script

Dependencies

GMMA code runs with Rscript version 4.0.2 or newer. Required packages: igraph, minpack.lm