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TODO
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TODO
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PROJECT DEPLOYMENT
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mvn -Dmaven.test.skip=true package
TODO
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DONE Gzip support
DONE Update Fork to Version 11.0 (git merge upstream/master)
DONE Inheritance Mode “Automatic (unknown)” als Default
DONE Add local DB
DONE Automatische Proband ID Auswahl falls nicht angegeben
TODO Parsing von Komma als Decimaldelimiter
TODO Add checkbox to analyse actionable genes only (see PMID27854360)
TODO Link to IGV ( via http://localhost:60151/goto?locus=chr17:73951701-73951721 )
TODO Link for Download of Results as XSLX File (incl. genes.tsv, variants.tsv & priorization)
TODO Depth Filter
TODO Filter for CRAP genes (Uwe Kornak: ESRRA, KCNJ11, HLA* und MUC*)
TODO Set Frequency sources by Checkbox (Talk to MVZ). Possible values are:
#Possible frequencySources:
#Thousand Genomes project http://www.1000genomes.org/
# THOUSAND_GENOMES,
#ESP project http://evs.gs.washington.edu/EVS/
# ESP_AFRICAN_AMERICAN, ESP_EUROPEAN_AMERICAN, ESP_ALL,
#ExAC project http://exac.broadinstitute.org/about
# EXAC_AFRICAN_INC_AFRICAN_AMERICAN, EXAC_AMERICAN,
# EXAC_SOUTH_ASIAN, EXAC_EAST_ASIAN,
# EXAC_FINNISH, EXAC_NON_FINNISH_EUROPEAN,
# EXAC_OTHER
#Possible frequencySources:
#Thousand Genomes project - http://www.1000genomes.org/ (THOUSAND_GENOMES)
#TOPMed - https://www.nhlbi.nih.gov/science/precision-medicine-activities (TOPMED)
#UK10K - http://www.uk10k.org/ (UK10K)
#ESP project - http://evs.gs.washington.edu/EVS/ (ESP_)
# ESP_AFRICAN_AMERICAN, ESP_EUROPEAN_AMERICAN, ESP_ALL,
#ExAC project http://exac.broadinstitute.org/about (EXAC_)
# EXAC_AFRICAN_INC_AFRICAN_AMERICAN, EXAC_AMERICAN,
# EXAC_SOUTH_ASIAN, EXAC_EAST_ASIAN,
# EXAC_FINNISH, EXAC_NON_FINNISH_EUROPEAN,
# EXAC_OTHER
#gnomAD - http://gnomad.broadinstitute.org/ (GNOMAD_E, GNOMAD_G)