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insulin_signaling

This repository provides access to the data and methods used for the comparative analysis of ant brain gene expression between reproductive and non-reproductive castes. This work was originally published in Chandra, V., Fetter-Pruneda, I. et al. Science (2018):

DOI

Social regulation of insulin signaling and the evolution of eusociality in ants

Vikram Chandra*(1), Ingrid Fetter-Pruneda*(1), Peter R. Oxley(1,2), Amelia L. Ritger(1), Sean K. McKenzie(1,3), Romain Libbrecht(1,4), Daniel J. C. Kronauer(1)

  1. Laboratory of Social Evolution and Behavior, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
  2. Samuel J. Wood Library, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA
  3. Department of Ecology and Evolution, University of Lausanne, Biophore Building, 1015 Lausanne, Switzerland
  4. Institute of Organismic and Molecular Evolution, Johannes Gutenberg University, Johannes-von-Müller-Weg 6, 55128 Mainz, Germany

* These authors contributed equally

Table of contents

  • README - this file
  • License - GNU public license
  • DESeq2_output - the differential gene expression values calculated for each of the seven species using DESeq2.
  • orthomcl_output - the mcl groups from analysis of 18 NCBI-annotated insect genomes
  • comparative_analysis - jupyter notebook showing the identification of concordant differentially expressed genes in seven ant species
  • Cpla_contamination_removal - jupyter notebook showing the pipeline to identify and remove contaminants from the Camponotus planatus transcriptome
  • Orug_contamination_removal - jupyter notebook showing the pipeline to identify and remove contaminants from the Odontomachus ruginodis transcriptome
  • clean_Cpla_txome - Predicted peptide sequences for each transcript in the cleaned Camponotus planatus transcriptome
  • clean_Orug_txome - Predicted peptide sequences for each transcript in the cleaned Odontomachus ruginodis transcriptome