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New functionality to compute the ED OFV using the Laplace approximation.
This can be orders of magnitude faster than the standard MC integration approach.
See ?ed_laplace_ofv and ?evaluate.e.ofv.fim
Added a general function to compute the FIM and OFV(FIM) for all avaialbale methods in PopED.
See ?calc_ofv_and_fim.
Added a general optimization algorithm RS_opt_gen() that works for both D-family and
E-family optimization.
Added optimization of E-family designs to poped_optimize().
Changed distribution tests for package building
Fixed bug where correlations between BSV (between subject variability) terms in the model gave an error when creating a PopED database
Fixed a bug where get_rse failed when a parameter had a value of 3.