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Learning Comlete Protein Representation by Deep Coupling of Sequence and Structure

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CoupleNet

Learning Complete Protein Representation by Deep Coupling of Sequence and Structure

File Specification

datasets.py gives some dataset functions to process data, including the amino acid types and the physicochemical properties of each residue, namely, a steric parameter, hydrophobicity, volume, polarizability, isoelectric point, helix probability, and sheet probability. Besides, the geometric features are included.

test_go.py gets the f_max for a single protein.

We publicize partial codes before acceptance.

Installation

Install PyTorch 1.13.1:

pip install torch==1.13.1+cu117 torchvision==0.14.1+cu117 torchaudio==0.13.1 --extra-index-url https://download.pytorch.org/whl/cu117

Install PyG, transformers:

pip install torch-geometric
pip install transformers

Install PyTorch Scatter and PyTorch Sparse:

pip install torch_scatter torch_sparse -f https://data.pyg.org/whl/torch-1.13.1+cu117.html

License

The code is released under MIT License.

Related Repos

  1. CDConv   2. GearNet

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Learning Comlete Protein Representation by Deep Coupling of Sequence and Structure

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