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HTAN_BRCA_publication

This a repo for manuscript "Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their cells of origin"


Repo structure

  • Fig1: Study Design, Data Collected, and Genomic Alterations.

  • Fig2: Tumor Subtype and Benign Duct Cell Types.

  • Fig3: Subtype-enriched Elements of the Tumor Microenvironment.

  • Fig4: Chromatin Accessibility Evidence for Subtype-specific Cell of Origin.

  • Fig5: Spatial Characterization of Tumor Subtype and Normal Ducts.

  • Fig6: Tumor Lineage-specific Regulators of Gene Expression.

  • Fig7: Differential Markers of Basal-like and Luminal Breast Cancer Lineage.

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