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DESCRIPTION
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Package: ScreenBEAM2
Type: Package
Title: A novel meta-analysis algorithm for functional genomics screens via Bayesian hierarchical modeling, Version 2
Version: 0.1.0
Author@R: person('Xinge', 'Wang', email = '[email protected]')
Author: Xinge Wang,
Chenxi Qian
Maintainer@R: person('Chenxi', 'Qian', email = '[email protected]')
Maintainer: Chenxi Qian<[email protected]>
Description: ScreenBEAM2 is the upgraded version of ScreenBEAM1. It can perform functional genomics screening from FASTQ file. It is a trim-free, allowing number of mismatch, BLAT-depend pipeline. Downstream analysis uses Bayesian hierarchical modeling, removed bias caused by the unbalanced number of sh/sgRNA targeting the same gene.
License: Apache License
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.1.0
Depends:
R (>= 3.6.0),
Biobase (>= 2.38.0),
readr (>= 1.3.1),
kableExtra (>= 1.1.0),
knitr (>= 1.24),
data.table (>= 1.12.2),
graphics,
grDevices,
plyr (>= 1.8.4)
Imports:
MCMCglmm (>= 2.29),
RColorBrewer (>= 1.1-2),
stats (>= 3.6.0),
stringr (>= 1.4.0),
tidyr,
dplyr (>= 0.8.0),
methods,
lme4,
rmarkdown (>= 2.1),
arm (>= 1.10.1)
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