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Dissociable Asymmetry Patterns

This repository contains all asymmetry patterns associated with our paper Dissociable brain structural asymmetry patterns reveal unique phenome-wide profiles.

Please cite the paper: Saltoun, K., Adolphs, R., Paul, L.K., Sharma V., Diedrichsen J., Yeo B.T.T, Bzdok D. Dissociable brain structural asymmetry patterns reveal unique phenome-wide profiles. Nat Hum Behav (2022). https://doi.org/10.1038/s41562-022-01461-0

Contents

Asymmetry patterns are located within the appropriately named folder.

Each asymmetry pattern folder contains the following:

  • Feature contributions which comprise the asymmetry pattern
    • Glass brain plots for each level of brain organization (cerebellum, white matter tracts, and grey matter volumes)
    • Exact feature contributions for all 85 brain features which contribute to the asymmetry pattern
  • Phenome-wide Association Study (PheWAS) Results
    • All phenotype associations (977) p values and associated phenotype
    • All phenotypes above the False Discovery Rate (FDR) Threshold, grouped by category
    • Manhattan Plots as a visual summary of PheWAS Results
  • Age/Sex Analysis

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