Skip to content

Commit

Permalink
fix issues #43 #44 and #45
Browse files Browse the repository at this point in the history
documentation fixes regarding "tdm=TRUE" in dosing optim functions
documentation fix regarding AUC duration
bug fix in dosing optim functions: estimates were always zero
  • Loading branch information
levenc committed Nov 24, 2023
1 parent cbd0a68 commit 08d42fd
Show file tree
Hide file tree
Showing 31 changed files with 767 additions and 602 deletions.
2 changes: 1 addition & 1 deletion DESCRIPTION
Original file line number Diff line number Diff line change
@@ -1,6 +1,6 @@
Package: posologyr
Title: Individual Dose Optimization using Population Pharmacokinetics
Version: 1.2.2
Version: 1.2.2.9000
Authors@R: c(
person("Cyril","Leven",role = c("aut", "cre","cph"),
email = "[email protected]",
Expand Down
9 changes: 9 additions & 0 deletions NEWS.md
Original file line number Diff line number Diff line change
@@ -1,3 +1,12 @@
# posologyr v1.2.2.9000

## Bug fix
* Fix a bug in `poso_dose_conc()`, `poso_dose_auc()` and `poso_inter_cmin()` where the returned estimate of the target value to be optimized against was always equal to zero.

## Documentation
* The documentation of `poso_time_cmin()`, `poso_dose_conc()`, `poso_dose_auc()` and `poso_inter_cmin()` now specifies which parameters are ignored when the value of `tdm` is set to `TRUE`, and the functions return a warning if input parameters are ignored.
* Fix incorrect information regarding the duration of the AUC in the documentation of `poso_dose_auc()`

# posologyr v1.2.2
* Relax the requirements of the NONMEM comparison test for time-varying covariates to account for computational differences observed with the alternative BLAS ATLAS on CRAN.

Expand Down
279 changes: 179 additions & 100 deletions R/dosing_optim.R

Large diffs are not rendered by default.

2 changes: 1 addition & 1 deletion docs/404.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

2 changes: 1 addition & 1 deletion docs/LICENSE.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

6 changes: 3 additions & 3 deletions docs/articles/a_posteriori_dosing.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

4 changes: 2 additions & 2 deletions docs/articles/a_priori_dosing.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

8 changes: 4 additions & 4 deletions docs/articles/auc_based_dosing.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

2 changes: 1 addition & 1 deletion docs/articles/index.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

22 changes: 11 additions & 11 deletions docs/articles/multiple_endpoints.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

2 changes: 1 addition & 1 deletion docs/articles/patient_data_input.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

4 changes: 2 additions & 2 deletions docs/articles/posologyr_user_defined_models.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

2 changes: 1 addition & 1 deletion docs/authors.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

2 changes: 1 addition & 1 deletion docs/index.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

15 changes: 14 additions & 1 deletion docs/news/index.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

2 changes: 1 addition & 1 deletion docs/pkgdown.yml
Original file line number Diff line number Diff line change
Expand Up @@ -8,5 +8,5 @@ articles:
multiple_endpoints: multiple_endpoints.html
patient_data_input: patient_data_input.html
posologyr_user_defined_models: posologyr_user_defined_models.html
last_built: 2023-09-24T13:40Z
last_built: 2023-11-24T21:04Z

2 changes: 1 addition & 1 deletion docs/reference/error_model_comb1.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

2 changes: 1 addition & 1 deletion docs/reference/error_model_comb2.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

2 changes: 1 addition & 1 deletion docs/reference/error_model_mixednm.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

2 changes: 1 addition & 1 deletion docs/reference/index.html

Some generated files are not rendered by default. Learn more about how customized files appear on GitHub.

Loading

0 comments on commit 08d42fd

Please sign in to comment.