Reorganize pseudobulk and deseq2 functions #300
Merged
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Modify
pseudobulk
function:sample
togroupby
cluster
tocondition
MultimodalData
object, and don't write to the original data objectattrs
to be categorical in the pseudobulk data objectModify
deseq2
function:_run_pydeseq2
and_run_rdeseq2
. Default is_run_pydeseq2
compute_all
parameter to decide if applying DE analysis to all count matricesalpha
parameter to allow user choose significance level for independent filtering to calculate adjusted p-valuesCompatible with matplotlib v3.9+:
legend.legendHandles
tolegend.legend_handles
, as v3.9+ removes legendHandles attribute.Improve
calc_dendrogram
function:rep
by usingupdate_rep
andX_from_rep
utility functions