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Amino acids for hypermutations and helper routines
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@mikessh mikessh released this 01 Feb 14:26
· 120 commits to master since this release
0.9.9
915666b

Improvements

  • Added amino acid representation for hypermutations: one-to-one correspondence for nucleotide representation, amino acid sequences are provided on cumulative level, i.e. a single effect is reported for sets of adjacent hypermutations.

Helper routines

  • Correct routine - applies a frequency + parsimony-based algorithm that traverses variant tree and appends erroneous variants to their parent clonotypes.
  • An option to use custom database and a routine to annotate custom reference file with so-called V/J reference points.
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