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pushed R21 profiles
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lmhaile committed Sep 9, 2024
1 parent 83375fe commit 6ecab00
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29 changes: 29 additions & 0 deletions R/pev_parameters.R
Original file line number Diff line number Diff line change
Expand Up @@ -42,6 +42,21 @@ rtss_profile <- create_pev_profile(
dl = c(6.30365, 0.396515) # (White MT et al. 2015 Lancet ID)
)

#' @title R21 vaccine profile
#' @description Parameters for a primary dose of R21 for use with the
#' set_mass_pev and set_pev_epi functions
#' @export
r21_profile <- create_pev_profile(
vmax = 0.87,
alpha = 0.91,
beta = 471,
cs = c(9.3199677, 0.8387902),
rho = c(0.8071676, 0.6010363),
ds = c(3.7996007, 0.1618982), # (Schmit + Topazian et al. 2022 Lancet ID)
dl = c(6.2820200, 0.4549185) # (Schmit + Topazian et al. 2022 Lancet ID)
)


#' @title RTS,S booster vaccine profile
#' @description Parameters for a booster dose of RTS,S for use with the
#' set_mass_pev and set_pev_epi functions
Expand All @@ -56,6 +71,20 @@ rtss_booster_profile <- create_pev_profile(
dl = c(6.30365, 0.396515) # (White MT et al. 2015 Lancet ID)
)

#' @title R21 booster vaccine profile
#' @description Parameters for a booster dose of R21 for use with the
#' set_mass_pev and set_pev_epi functions
#' @export
r21_booster_profile <- create_pev_profile(
vmax = 0.87,
alpha = 0.91,
beta = 471,
cs = c(9.2372858, 0.7188541),
rho = c(0.07140337, 0.54175154),
ds = c(3.7996007, 0.1618982), # (Schmit + Topazian et al. 2022 Lancet ID)
dl = c(6.2820200, 0.4549185) # (Schmit + Topazian et al. 2022 Lancet ID)
)

#' @title Parameterise a pre-erythrocytic vaccine with an EPI strategy
#'
#' @description distribute vaccine when an individual becomes a certain
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