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Add R21 PEV profiles #333

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Sep 12, 2024
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4 changes: 2 additions & 2 deletions .github/workflows/pkgdown.yml
Original file line number Diff line number Diff line change
Expand Up @@ -13,9 +13,9 @@ jobs:
steps:
- uses: actions/checkout@v2

- uses: r-lib/actions/setup-r@v1
- uses: r-lib/actions/setup-r@v2

- uses: r-lib/actions/setup-pandoc@v1
- uses: r-lib/actions/setup-pandoc@v2

- name: Query dependencies
run: |
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2 changes: 1 addition & 1 deletion DESCRIPTION
Original file line number Diff line number Diff line change
Expand Up @@ -91,7 +91,7 @@ Suggests:
ggplot2,
covr,
mgcv
RoxygenNote: 7.3.1
RoxygenNote: 7.3.2
Roxygen: list(markdown = TRUE)
LinkingTo:
Rcpp,
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2 changes: 2 additions & 0 deletions NAMESPACE
Original file line number Diff line number Diff line change
Expand Up @@ -13,6 +13,8 @@ export(get_parameters)
export(parameterise_mosquito_equilibrium)
export(parameterise_total_M)
export(peak_season_offset)
export(r21_booster_profile)
export(r21_profile)
export(rtss_booster_profile)
export(rtss_profile)
export(run_metapop_simulation)
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41 changes: 35 additions & 6 deletions R/pev_parameters.R
Original file line number Diff line number Diff line change
Expand Up @@ -30,30 +30,59 @@ create_pev_profile <- function(vmax, alpha, beta, cs, rho, ds, dl) {

#' @title RTS,S vaccine profile
#' @description Parameters for a primary dose of RTS,S for use with the
#' set_mass_pev and set_pev_epi functions
#' set_mass_pev and set_pev_epi functions (White MT et al. 2015 Lancet ID)
#' @export
rtss_profile <- create_pev_profile(
vmax = 0.93,
alpha = 0.74,
beta = 99.4,
cs = c(6.37008, 0.35),
rho = c(2.37832, 1.00813),
ds = c(3.74502, 0.341185), # (White MT et al. 2015 Lancet ID)
dl = c(6.30365, 0.396515) # (White MT et al. 2015 Lancet ID)
ds = c(3.74502, 0.341185),
dl = c(6.30365, 0.396515)
)

#' @title R21 vaccine profile
#' @description Parameters for a primary dose of R21 for use with the
#' set_mass_pev and set_pev_epi functions (Schmit + Topazian et al. 2022 Lancet ID)
#' @export
r21_profile <- create_pev_profile(
vmax = 0.87,
alpha = 0.91,
beta = 471,
cs = c(9.3199677, 0.8387902),
rho = c(0.8071676, 0.6010363),
ds = c(3.7996007, 0.1618982),
dl = c(6.2820200, 0.4549185)
)


#' @title RTS,S booster vaccine profile
#' @description Parameters for a booster dose of RTS,S for use with the
#' set_mass_pev and set_pev_epi functions
#' set_mass_pev and set_pev_epi functions (White MT et al. 2015 Lancet ID)
#' @export
rtss_booster_profile <- create_pev_profile(
vmax = 0.93,
alpha = 0.74,
beta = 99.4,
cs = c(5.56277, 0.35),
rho = c(1.03431, 1.02735),
ds = c(3.74502, 0.341185), # (White MT et al. 2015 Lancet ID)
dl = c(6.30365, 0.396515) # (White MT et al. 2015 Lancet ID)
ds = c(3.74502, 0.341185),
dl = c(6.30365, 0.396515)
)

#' @title R21 booster vaccine profile
#' @description Parameters for a booster dose of R21 for use with the
#' set_mass_pev and set_pev_epi functions (Schmit + Topazian et al. 2022 Lancet ID)
#' @export
r21_booster_profile <- create_pev_profile(
vmax = 0.87,
alpha = 0.91,
beta = 471,
cs = c(9.2372858, 0.7188541),
rho = c(0.07140337, 0.54175154),
ds = c(3.7996007, 0.1618982),
dl = c(6.2820200, 0.4549185)
)

#' @title Parameterise a pre-erythrocytic vaccine with an EPI strategy
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2 changes: 2 additions & 0 deletions _pkgdown.yml
Original file line number Diff line number Diff line change
Expand Up @@ -62,6 +62,8 @@ reference:
contents:
- set_species
- set_carrying_capacity
- calculate_carrying_capacity
- get_init_carrying_capacity
- arab_params
- fun_params
- gamb_params
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17 changes: 17 additions & 0 deletions man/r21_booster_profile.Rd

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17 changes: 17 additions & 0 deletions man/r21_profile.Rd

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2 changes: 1 addition & 1 deletion man/rtss_booster_profile.Rd

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2 changes: 1 addition & 1 deletion man/rtss_profile.Rd

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