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jykr committed Mar 30, 2024
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`bean` subcommands include the following:
1. [`count`](https://pinellolab.github.io/crispr-bean/count.html), [`count-samples`](https://pinellolab.github.io/crispr-bean/count_samples.html): Base-editing-aware **mapping** of guide, optionally with reporter from `.fastq` files.
* [`create-screen`](#bean-create-screen-create-reporterscreen-object-from-flat-files) creates minimal ReporterScreen object from flat gRNA count file. Note that this way, allele counts are not included and many functionalities involving allele and edit counts are not supported.
* [`create-screen`](https://pinellolab.github.io/crispr-bean/create_screen.html) creates minimal ReporterScreen object from flat gRNA count file. Note that this way, allele counts are not included and many functionalities involving allele and edit counts are not supported.
2. [`profile`](https://pinellolab.github.io/crispr-bean/profile.html): Profile editing preferences of your editor.
3. [`qc`](#bean-qc-qc-of-reporter-screen-data): Quality control report and filtering out / masking of aberrant sample and guides
4. [`filter`](#bean-filter-filtering-and-optionally-translating-alleles): Filter reporter alleles; essential for `tiling` mode that allows for all alleles generated from gRNA.
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