Mitonuclear Genotype Remodels the Metabolic and Microenvironmental Landscape of Hurthle Cell Carcinoma

References

• Ian Ganly*, Eric Minwei Liu*, Fengshen Kuo, Vladimir Makarov, Yiyu Dong, Jinsung Park, Yongxing Gong, Alexander N. Gorelick, Jeffrey A Knauf, Elisa Benedetti, Jacqueline Tait-Mulder, Luc G.T. Morris, James A. Fagin, Andrew M Intlekofer, Jan Krumsiek, Payam A. Gammage, Ronald Ghossein, Bin Xu, Timothy A. Chan#, Ed Reznik# "Mitonuclear Genotype Remodels the Metabolic and Microenvironmental Landscape of Hurthle Cell Carcinoma" (2022)

Overview

Analysis scripts for Ganly and Liu et al.(2022)

Requirements

• R version 4.1.0 -- "Camp Pontanezen"

Getting started

1. Clone this repo:

git clone https://github.com/reznik-lab/hurthle-cell-carcinoma-integrated-analysis
cd hurthle-cell-carcinoma-integrated-analysis

2. Running the scripts in the R folder to generate relevant figures of the study.

Contacts

For any questions, comments and suggestions, please email

• Ed Reznik, reznike [at] mskcc.org
• Eric Minwei Liu, lium2 [at] mskcc.org