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genetic-interactions

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PAGER is an efficient genotype encoding strategy designed to improve the detection of non-additive genetic variation in complex trait association studies and epistasis investigation. PAGER dynamically encodes genetic variants or multi-locus genotypes (MLG) by normalizing mean phenotypic differences between genotype/MLG classes.

  • Updated Oct 16, 2024
  • Python

PAGER is an efficient genotype encoding strategy designed to improve the detection of non-additive genetic variation in complex trait association studies and epistasis investigation. PAGER dynamically encodes genetic variants or multi-locus genotypes (MLG) by normalizing mean phenotypic differences between genotype/MLG classes.

  • Updated Oct 25, 2024
  • Python

The functional analysis of genes provides relevant information to understand cellular function. Further, the mapping of genetic interactions sheds light on how genes act in the emergence of cellular complexity. Here, we present the most extensive genetic interaction and morphological profiling screen in a metazoan cell to date. We profiled 680 0…

  • Updated May 17, 2023
  • HTML

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