Sex-dependent placental mQTL provide insight into the prenatal origins of childhood-onset traits and conditions

Code and notebooks corresponding to analysis done in the above titled publication ¹. mQTL summary statistics and related annotations can be found on this Open Science Framework site.

Directory structure

• NICHD quality control for DNA methylation and genotyping
• RICHS quality control for DNA methylation and genotyping
• Analysis code for publication
  • main results figures and data processing
  • Supporting R scripts
  • Supporting TORQUE/MOAB scripts, written in bash

Environment file

All packages used in this project are included in the environment.yml file. They can be installed using anaconda

Footnotes

1. William Casazza, Amy M. Inkster, Giulia F. Del Gobbo, Victor Yuan, Fabien Delahaye, Carmen Marsit, Yongjin P. Park, Wendy P. Robinson, Sara Mostafavi, Jessica K. Dennis. Sex-dependent placental mQTL provide insight into the prenatal origins of childhood onset traits and conditions. iScience, 2024. https://doi.org/10.1016/j.isci.2024.109047 ↩