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normalize-by-median.py | ||
normalize-iHS | ||
nquire | ||
ntedit | ||
nucmer | ||
nullarbor.pl | ||
octopus | ||
|
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{"name":"ntedit","description":"Fast, lightweight, scalable genome sequence polishing and SNV detection & annotation","usage":"","options":[{"names":["-t"],"argument":"NUM","description":"number of threads [default=1]"},{"names":["-f"],"argument":"FILE","description":"draft genome assembly (FASTA, Multi-FASTA, and/or gzipped compatible), REQUIRED"},{"names":["-r"],"argument":"FILE","description":"Bloom filter file (generated from ntHits), REQUIRED"},{"names":["-e"],"argument":"FILE","description":"secondary Bloom filter with k-mers to reject (generated from ntHits), OPTIONAL"},{"names":["-b"],"argument":"STR","description":"output file prefix, OPTIONAL"},{"names":["-z"],"argument":"NUM","description":"minimum contig length [default=100]"},{"names":["-i"],"argument":"NUM","description":"maximum number of insertion bases to try, range 0-5, [default=5]"},{"names":["-d"],"argument":"NUM","description":"maximum number of deletions bases to try, range 0-10, [default=5]"},{"names":["-x"],"argument":"NUM","description":"k/x ratio for the number of k-mers that should be missing, [default=5.000]"},{"names":["-y"],"argument":"NUM","description":"k/y ratio for the number of edited k-mers that should be present, [default=9.000]"},{"names":["-X"],"argument":"NUM","description":"ratio of number of k-mers in the k subset that should be missing in order to attempt fix (higher=stringent), [default=0.5]"},{"names":["-Y"],"argument":"NUM","description":"ratio of number of k-mers in the k subset that should be present to accept an edit (higher=stringent), [default=0.5]"},{"names":["-c"],"argument":"NUM","description":"cap for the number of base insertions that can be made at one position, [default=k*1.5]"},{"names":["-j"],"argument":"NUM","description":"controls size of k-mer subset. When checking subset of k-mers, check every jth k-mer, [default=3]"},{"names":["-m"],"argument":"{0,1,2}","description":"mode of editing, range 0-2, [default=0] 0: best substitution, or first good indel 1: best substitution, or best indel 2: best edit overall (suggestion that you reduce i and d for performance)"},{"names":["-s"],"argument":"{0,1}","description":"SNV mode. Overrides draft k-mer checks, forcing reassessment at each position (-s 1 = yes, default = 0, no)"},{"names":["-l"],"argument":"FILE","description":"input VCF file with annotated variants (e.g., clinvar.vcf), OPTIONAL"},{"names":["-a"],"argument":"{0,1}","description":"soft masks missing k-mer positions having no fix (-v 1 = yes, default = 0, no)"},{"names":["-v"],"argument":"{0,1}","description":"verbose mode (-v 1 = yes, default = 0, no)"},{"names":["--help"],"argument":"","description":"display this message and exit"},{"names":["--version"],"argument":"","description":"output version information and exit"}],"version":"ntEdit v1.4.3"} |
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name: ntedit | ||
description: Fast, lightweight, scalable genome sequence polishing and SNV detection & annotation | ||
usage: "" | ||
options: | ||
- names: | ||
- -t | ||
argument: NUM | ||
description: number of threads [default=1] | ||
- names: | ||
- -f | ||
argument: FILE | ||
description: draft genome assembly (FASTA, Multi-FASTA, and/or gzipped compatible), REQUIRED | ||
- names: | ||
- -r | ||
argument: FILE | ||
description: Bloom filter file (generated from ntHits), REQUIRED | ||
- names: | ||
- -e | ||
argument: FILE | ||
description: secondary Bloom filter with k-mers to reject (generated from ntHits), OPTIONAL | ||
- names: | ||
- -b | ||
argument: STR | ||
description: output file prefix, OPTIONAL | ||
- names: | ||
- -z | ||
argument: NUM | ||
description: minimum contig length [default=100] | ||
- names: | ||
- -i | ||
argument: NUM | ||
description: maximum number of insertion bases to try, range 0-5, [default=5] | ||
- names: | ||
- -d | ||
argument: NUM | ||
description: maximum number of deletions bases to try, range 0-10, [default=5] | ||
- names: | ||
- -x | ||
argument: NUM | ||
description: k/x ratio for the number of k-mers that should be missing, [default=5.000] | ||
- names: | ||
- -y | ||
argument: NUM | ||
description: k/y ratio for the number of edited k-mers that should be present, [default=9.000] | ||
- names: | ||
- -X | ||
argument: NUM | ||
description: ratio of number of k-mers in the k subset that should be missing in order to attempt fix (higher=stringent), [default=0.5] | ||
- names: | ||
- -Y | ||
argument: NUM | ||
description: ratio of number of k-mers in the k subset that should be present to accept an edit (higher=stringent), [default=0.5] | ||
- names: | ||
- -c | ||
argument: NUM | ||
description: cap for the number of base insertions that can be made at one position, [default=k*1.5] | ||
- names: | ||
- -j | ||
argument: NUM | ||
description: controls size of k-mer subset. When checking subset of k-mers, check every jth k-mer, [default=3] | ||
- names: | ||
- -m | ||
argument: '{0,1,2}' | ||
description: 'mode of editing, range 0-2, [default=0] 0: best substitution, or first good indel 1: best substitution, or best indel 2: best edit overall (suggestion that you reduce i and d for performance)' | ||
- names: | ||
- -s | ||
argument: "{0,1}" | ||
description: SNV mode. Overrides draft k-mer checks, forcing reassessment at each position (-s 1 = yes, default = 0, no) | ||
- names: | ||
- -l | ||
argument: FILE | ||
description: input VCF file with annotated variants (e.g., clinvar.vcf), OPTIONAL | ||
- names: | ||
- -a | ||
argument: '{0,1}' | ||
description: soft masks missing k-mer positions having no fix (-v 1 = yes, default = 0, no) | ||
- names: | ||
- -v | ||
argument: '{0,1}' | ||
description: verbose mode (-v 1 = yes, default = 0, no) | ||
- names: | ||
- --help | ||
argument: "" | ||
description: display this message and exit | ||
- names: | ||
- --version | ||
argument: "" | ||
description: output version information and exit | ||
version: ntEdit v1.4.3 |