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gbanco4 edited this page Dec 18, 2024 · 17 revisions

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

[[TOC]]

Overview

Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.[@reddyGeneticFunctionalDrivers2017] Subsequent exome and genome-wide studies of DLBCL did not reproduce this observation.

Relevance tier by entity

Entity Tier Description
DLBCL 2 relevance in DLBCL not firmly established[@reddyGeneticFunctionalDrivers2017]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 1.15
DLBCL Schmitz cohort 1.70
DLBCL Reddy cohort 2.80
DLBCL Chapuy cohort 2.99

Mutation pattern and selective pressure estimates

include:dnds_CD22.md

include:browser_CD22.md

Expression

include:mermaid_CD22.md

References

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