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Ryan Morin edited this page Dec 16, 2024 · 22 revisions

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

[[TOC]]

Relevance tier by entity

Entity Tier Description
DLBCL 2 relevance in DLBCL not firmly established[@chapuyMolecularSubtypesDiffuse2018]
MCL 1 high-confidence MCL gene [@beaLandscapeSomaticMutations2013]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 2.87
DLBCL Schmitz cohort 2.77
DLBCL Reddy cohort 1.50
DLBCL Chapuy cohort 2.99
MCL GAMBL genomes 0.00

Mutation pattern and selective pressure estimates

include:dnds_TLR2.md

TLR2 Hotspots

Chromosome Coordinate (hg19) ref>alt HGVSp
chr4 154625039 A>T D327V
chr4 154625042 T>G L328R

include:browser_TLR2.md

Expression

All Mutations

DLBCL-RICOVER_1269-Tumor DLBCL-RICOVER_174-Tumor

include:mermaid_TLR2.md

References

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