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gbanco4 edited this page Dec 17, 2024 · 19 revisions

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

[[TOC]]

Relevance tier by entity

Entity Tier Description
DLBCL 2 aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous [@reddyGeneticFunctionalDrivers2017]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 0.57
DLBCL Schmitz cohort 3.62
DLBCL Reddy cohort 2.10
DLBCL Chapuy cohort 2.99

Mutation pattern and selective pressure estimates

include:dnds_FOXP1.md

aSHM regions

chr_name hg19_start hg19_end region regulatory_comment
chr3 71104986 71119518 TSS-4 active_promoter
chr3 71176427 71180960 TSS-3 active_promoter
chr3 71350633 71357665 TSS-2 active_promoter
chr3 71503103 71504870 intron-1B intron
chr3 71550753 71551478 intron-1A intron
chr3 71626341 71635648 TSS-1 active_promoter

include:browser_FOXP1.md

Expression

include:mermaid_FOXP1.md

References

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