Skip to content

HIST1H1C

rdmorin edited this page May 19, 2024 · 32 revisions

HIST1H1C

Relevance tier by entity

Entity Tier Description
BL 2 relevance in BL not firmly established
DLBCL 1 high-confidence DLBCL gene
FL 1 high-confidence FL gene

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
BL GAMBL genomes+capture 4.85
BL Thomas cohort 3.80
BL Panea cohort 9.90
DLBCL GAMBL genomes 9.94
DLBCL Schmitz cohort 9.79
DLBCL Reddy cohort 9.41
DLBCL Chapuy cohort 12.39
FL GAMBL genomes 5.08

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 10.205 0
DLBCL No Yes 9.354 0
FL No No 4.446 0

Note

First described in BL in 2019 by Panea RI. First described in DLBCL in 2011 by Morin RD. First described in FL in 2011 by Morin RD

View coding variants in ProteinPaint hg19 or hg38

image

View all variants in GenomePaint hg19 or hg38

image

Disclaimer

The content in these pages has been populated, in part, by an automated process. Although we have scrutinized every page to ensure accuracy, errors will inevitably exist. If you find an error please report it as an issue and we will address it.

In particular, let us know if you feel that an important citation is missing or if a paper has been cited incorrectly.

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

You are free to:

Share — copy and redistribute the material in any medium or format for any purpose, even commercially.

Adapt — remix, transform, and build upon the material for any purpose, even commercially. The licensor cannot revoke these freedoms as long as you follow the license terms.

Clone this wiki locally