HIST1H3D

HIST1H3D

History

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timeline
    title Publication timing
      2019-09-26 : Panea : BL

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Relevance tier by entity

Entity	Tier	Description
	2	relevance in BL not firmly established

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
BL	GAMBL genomes+capture	2.31
BL	Thomas cohort	1.70
BL	Panea cohort	3.00

Mutation pattern and selective pressure estimates

Entity	aSHM	Significant selection	dN/dS (missense)	dN/dS (nonsense)
BL	No	No	2.566	0
DLBCL	No	No	2.153	0
FL	No	No	0.000	0

HIST1H3D Hotspots

Chromosome	Coordinate (hg19)	ref>alt	HGVSp
chr6	26197218	G>C	S87R
chr6	26197219	C>G	S87T
chr6	26197219	C>T	S87N

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

HIST1H3D Expression

References

1. Panea R, Love C, Shingleton JR, Reddy A, Bailey J, Moormann A, Otieno J, Ong’echa J, Oduor C, Schroêder K, Masalu N, Chao N, Agajanian M, Major M, Fedoriw Y, Richards K, Rymkiewicz G, Miles R, Alobeid B, Bhagat G, Flowers C, Ondrejka S, Hsi E, Choi W, Au-Yeung R, Hartmann W, Lenz G, Meyerson H, Lin YY, Zhuang Y, Luftig M, Waldrop A, Dave T, Thakkar D, Sahay H, Li G, Palus B, Seshadri V, Kim S, Gascoyne R, Levy S, Mukhopadhyay M, Dunson D, Dave S. The whole genome landscape of Burkitt lymphoma subtypes. Blood. 2019;