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rdmorin edited this page Apr 19, 2024 · 22 revisions

[IGLL5]

Mutation tier

Entity Tier
BL 2
DLBCL 2
FL 2

Mutation incidence

Entity study frequency (%)
BL GAMBL genomes+capture 26.33
BL Thomas cohort 25.00
BL Panea cohort 23.80
DLBCL GAMBL genomes 41.10
DLBCL Schmitz cohort 36.00
DLBCL Reddy cohort 16.10
DLBCL Chapuy cohort 9.00
FL GAMBL genomes 35.33

Mutation pattern

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL Yes Yes 7.850 3.210
DLBCL Yes Yes 3.376 5.315
FL Yes Yes 4.830 9.846

aSHM regions

chr_name hg19_start hg19_end region regulatory_comment
chr22 23229554 23232042 TSS NA

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