Skip to content

MZL_genes

Jump to bottom
rdmorin edited this page Jun 8, 2024 · 11 revisions

title: 'MZL genes' bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

Origins of MZL genes

---
config:
  sankey:
    showValues: false
    linkColor: target
    width: 800
    height: 750
    nodeAlignment: right
---
sankey-beta
Vandenbrand 2017, Tier 2 MZL genes, 2
Rossi 2012, Tier 1 MZL genes, 10
Rossi 2012, Tier 2 MZL genes, 11
Yan 2012, Tier 1 MZL genes, 2
Parry 2013, Tier 2 MZL genes, 7
Spina 2016, Tier 1 MZL genes, 8
Spina 2016, Tier 2 MZL genes, 23
Jallades 2017, Tier 1 MZL genes, 2
Jallades 2017, Tier 2 MZL genes, 26
Rossi 2011, Tier 1 MZL genes, 4
Rossi 2011, Tier 2 MZL genes, 1
MZL genes, MZL-exome, 28
MZL-exome, Jallades 2017, 28
MZL genes, MZL-Sanger, 5
MZL-Sanger, Rossi 2011, 5
MZL genes, MZL-exome/panel, 31
MZL-exome/panel, Spina 2016, 31
MZL genes, MZL-exome, 21
MZL-exome, Rossi 2012, 21
MZL genes, MZL-panel, 2
MZL-panel, Vandenbrand 2017, 2
MZL genes, MZL-Panel, 2
MZL-Panel, Yan 2012, 2
MZL genes, MZL-exome, 7
MZL-exome, Parry 2013, 7
Loading

Tier 1 MZL genes

42 total

Gene Tier First MZL evidence Other entities
ACTB 1 [@lohrDiscoveryPrioritizationSomatic2012a; @wienandGenomicAnalysesFlowsorted2019b]
ARID1A 1 [@rossiCodingGenomeSplenic2012c] [@krysiakRecurrentSomaticMutations2017b; @loveGeneticLandscapeMutations2012; @zhangGeneticHeterogeneityDiffuse2013; @wienandGenomicAnalysesFlowsorted2019b]
ATM 1 [@braggioGenomicAnalysisMarginal2012] [@reddyGeneticFunctionalDrivers2017; @beaLandscapeSomaticMutations2013]
BCL10 1 [@spinaGeneticsNodalMarginal2016b] [@russler-germainMutationsAssociatedProgression2023b; @morinFrequentMutationHistonemodifying2011]
BCL7A 1 [@grandeGenomewideDiscoverySomatic2019; @krysiakRecurrentSomaticMutations2017b; @reichelFlowSortingExome2015a; @arthurGenomewideDiscoverySomatic2018]
BIRC3 1 [@rossiAlterationBIRC3Multiple2011a] [@arthurGenomewideDiscoverySomatic2018; @beaLandscapeSomaticMutations2013; @dunsCharacterizationDLBCLPMBL2021b]
BRAF 1 [@tiacciBRAFMutationsHairycell2011a; @loveGeneticLandscapeMutations2012]
BTG1 1 [@sarkozyMutationalLandscapeGray2021a; @morinFrequentMutationHistonemodifying2011; @burkhardtClinicalRelevanceMolecular2022b]
CARD11 1 [@yanBCRTLRSignaling2012a] [@lenzOncogenicCARD11Mutations2008; @wuGeneticHeterogeneityPrimary2016; @morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]
CCND3 1 [@jalladesExomeSequencingIdentifies2017] [@deschGenotypingCirculatingTumor2020; @richterRecurrentMutationID32012a; @morinFrequentMutationHistonemodifying2011]
CXCR4 1 [@paneaWholeGenomeLandscape2019; @krysiakRecurrentSomaticMutations2017b; @khodabakhshiRecurrentTargetsAberrant2012]
DTX1 1 [@rossiCodingGenomeSplenic2012c] [@schmitzGeneticsPathogenesisDiffuse2018a; @gomezUltraDeepSequencingReveals2023; @paneaWholeGenomeLandscape2019]
EP300 1 [@rossiCodingGenomeSplenic2012c] [@pasqualucciInactivatingMutationsAcetyltransferase2011a; @paneaWholeGenomeLandscape2019]
EZH2 1 [@loveGeneticLandscapeMutations2012; @morinSomaticMutationsAltering2010a; @mottokIntegrativeGenomicAnalysis2019b]
FAS 1 [@spinaGeneticsNodalMarginal2016b] [@schollMutationsRegionFAS2007]
FAT1 1 [@spinaGeneticsNodalMarginal2016b]
FOXO1 1 [@dunsCharacterizationDLBCLPMBL2021b; @morinFrequentMutationHistonemodifying2011; @schmitzBurkittLymphomaPathogenesis2012]
H1-4 1
H1-5 1
ID3 1 [@spinaGeneticsNodalMarginal2016b] [@richterRecurrentMutationID32012a; @schmitzBurkittLymphomaPathogenesis2012]
KLF2 1 [@jalladesExomeSequencingIdentifies2017] [@deschGenotypingCirculatingTumor2020; @pasqualucciAnalysisCodingGenome2011]
KLHL6 1 [@ganapathiGeneticLandscapeDural2016] [@paneaWholeGenomeLandscape2019; @morinFrequentMutationHistonemodifying2011]
KMT2D 1 [@rossiCodingGenomeSplenic2012c] [@deschGenotypingCirculatingTumor2020; @grandeGenomewideDiscoverySomatic2019; @beaLandscapeSomaticMutations2013; @morinFrequentMutationHistonemodifying2011]
MAP3K14 1 [@rossiAlterationBIRC3Multiple2011a] [@ottoGeneticLesionsTRAF32012a]
MPEG1 1 [@morinMutationalStructuralAnalysis2013]
MYD88 1 [@yanBCRTLRSignaling2012a] [@ngoOncogenicallyActiveMYD882011a]
NCOR2 1 [@spinaGeneticsNodalMarginal2016b] [@schmitzBurkittLymphomaPathogenesis2012; @sarkozyMutationalLandscapeGray2021a]
NOL9 1 [@spinaGeneticsNodalMarginal2016b] [@schmitzGeneticsPathogenesisDiffuse2018a]
NOTCH1 1 [@rossiCodingGenomeSplenic2012c] [@loveGeneticLandscapeMutations2012; @beaLandscapeSomaticMutations2013; @pasqualucciAnalysisCodingGenome2011]
NOTCH2 1 [@rossiCodingGenomeSplenic2012c] [@paneaWholeGenomeLandscape2019; @beaLandscapeSomaticMutations2013; @troenNOTCH2MutationsMarginal2008]
PCLO 1 [@lohrDiscoveryPrioritizationSomatic2012a]
POU2AF1 1 [@krysiakRecurrentSomaticMutations2017b]
PTPRD 1 [@spinaGeneticsNodalMarginal2016b]
SIN3A 1 [@rossiCodingGenomeSplenic2012c] [@grandeGenomewideDiscoverySomatic2019]
SOCS1 1 [@morinFrequentMutationHistonemodifying2011; @wenigerMutationsTumorSuppressor2006a]
SPEN 1 [@rossiCodingGenomeSplenic2012c] [@sarkozyMutationalLandscapeGray2021a]
STAT6 1 [@yildizActivatingSTAT6Mutations2015c; @ritzRecurrentMutationsSTAT62009a]
TBL1XR1 1 [@rossiCodingGenomeSplenic2012c] [@mareschalWholeExomeSequencing2016]
TNFAIP3 1 [@rossiAlterationBIRC3Multiple2011a] [@compagnoMutationsMultipleGenes2009a; @schmitzTNFAIP3A20Tumor2009a]
TNFRSF14 1 [@spinaGeneticsNodalMarginal2016b] [@morinFrequentMutationHistonemodifying2011; @cheungAcquiredTNFRSF14Mutations2010a]
TP53 1 [@rossiCodingGenomeSplenic2012c] [@beaLandscapeSomaticMutations2013; @morinFrequentMutationHistonemodifying2011; @wildaInactivationARFMDM2p53Pathway2004; @tiacciPervasiveMutationsJAKSTAT2018b]
TRAF3 1 [@rossiAlterationBIRC3Multiple2011a] [@ottoGeneticLesionsTRAF32012a; @pasqualucciAnalysisCodingGenome2011]

Tier 2 MZL genes

74 total

Gene Tier First MZL evidence Other entities
ABCA13 2 [@spinaGeneticsNodalMarginal2016b] [@sarkozyMutationalLandscapeGray2021a]
ACTG1 2 [@spinaGeneticsNodalMarginal2016b] [@hubschmannMutationalMechanismsShaping2021b; @deschGenotypingCirculatingTumor2020]
ADD2 2 [@spinaGeneticsNodalMarginal2016b]
AMN 2 [@spinaGeneticsNodalMarginal2016b]
AMOTL1 2 [@parryWholeExomeSequencing2013]
AOC2 2 [@spinaGeneticsNodalMarginal2016b]
ARHGAP20 2 [@jalladesExomeSequencingIdentifies2017]
ARHGEF15 2 [@jalladesExomeSequencingIdentifies2017]
ARHGEF17 2 [@jalladesExomeSequencingIdentifies2017]
BCOR 2 [@jalladesExomeSequencingIdentifies2017] [@nadeuGenomicEpigenomicInsights2020b]
C6orf103 2 [@spinaGeneticsNodalMarginal2016b]
CBFA2T3 2 [@parryWholeExomeSequencing2013]
CD79A 2 [@rossiCodingGenomeSplenic2012c] [@burkhardtClinicalRelevanceMolecular2022b]
CD9B 2 [@vandenbrandRecurrentMutationsGenes2017]
CDC42BPB 2 [@spinaGeneticsNodalMarginal2016b]
CDKN2A 2 [@spinaGeneticsNodalMarginal2016b] [@grandeGenomewideDiscoverySomatic2019; @morinMutationalStructuralAnalysis2013]
CLGN 2 [@spinaGeneticsNodalMarginal2016b]
CNKSR2 2 [@spinaGeneticsNodalMarginal2016b]
CREBBP 2 [@parryWholeExomeSequencing2013] [@loveGeneticLandscapeMutations2012; @dunsCharacterizationDLBCLPMBL2021b; @pasqualucciInactivatingMutationsAcetyltransferase2011a]
DNAH5 2 [@jalladesExomeSequencingIdentifies2017] [@morinMutationalStructuralAnalysis2013]
DNAH7 2 [@jalladesExomeSequencingIdentifies2017]
DNAI1 2 [@jalladesExomeSequencingIdentifies2017]
DOCK6 2 [@jalladesExomeSequencingIdentifies2017]
DSP 2
DTNB 2
DTX3L 2 [@jalladesExomeSequencingIdentifies2017]
EGR1 2 [@rossiCodingGenomeSplenic2012c] [@krysiakRecurrentSomaticMutations2017b; @reichelFlowSortingExome2015a]
EGR2 2 [@rossiCodingGenomeSplenic2012c]
EZH1 2 [@jalladesExomeSequencingIdentifies2017]
FAT4 2 [@parryWholeExomeSequencing2013] [@morinMutationalStructuralAnalysis2013; @zhangGenomicLandscapeMantle2014]
FBXO11 2 [@parryWholeExomeSequencing2013] [@hubschmannMutationalMechanismsShaping2021b; @richterRecurrentMutationID32012a]
GPR98 2 [@spinaGeneticsNodalMarginal2016b]
GPS2 2 [@rossiCodingGenomeSplenic2012c]
HIST1H1D 2 [@jalladesExomeSequencingIdentifies2017] [@krysiakRecurrentSomaticMutations2017b; @morinMutationalStructuralAnalysis2013]
HIST1H2AD 2 [@jalladesExomeSequencingIdentifies2017]
HIST1H2AG 2 [@rossiCodingGenomeSplenic2012c] [@morinMutationalStructuralAnalysis2013; @krysiakRecurrentSomaticMutations2017b; @paneaWholeGenomeLandscape2019]
HIST1H2BK 2 [@rossiCodingGenomeSplenic2012c] [@paneaWholeGenomeLandscape2019]
HIST4H4 2 [@jalladesExomeSequencingIdentifies2017]
HRAS 2 [@jalladesExomeSequencingIdentifies2017] [@reddyGeneticFunctionalDrivers2017]
IKBKB 2 [@rossiAlterationBIRC3Multiple2011a] [@reddyGeneticFunctionalDrivers2017; @wienandGenomicAnalysesFlowsorted2019b]
KAT6A 2 [@jalladesExomeSequencingIdentifies2017]
KDM6A 2 [@jalladesExomeSequencingIdentifies2017]
KIF26A 2 [@jalladesExomeSequencingIdentifies2017]
LRP1B 2 [@spinaGeneticsNodalMarginal2016b]
MCRS1 2 [@rossiCodingGenomeSplenic2012c]
MGA 2 [@jalladesExomeSequencingIdentifies2017] [@zhangGeneticHeterogeneityDiffuse2013]
MSL2 2 [@rossiCodingGenomeSplenic2012c]
MYC 2 [@jalladesExomeSequencingIdentifies2017] [@dunsCharacterizationDLBCLPMBL2021b; @pasqualucciHypermutationMultipleProtooncogenes2001a; @johnstonCmycHypermutationBurkitt1992]
MYLK 2 [@jalladesExomeSequencingIdentifies2017]
NCOA6 2 [@jalladesExomeSequencingIdentifies2017]
NRAS 2 [@jalladesExomeSequencingIdentifies2017]
PACRG 2 [@spinaGeneticsNodalMarginal2016b]
PARK2 2 [@spinaGeneticsNodalMarginal2016b]
PLA2G4D 2 [@parryWholeExomeSequencing2013]
PLXNB3 2 [@spinaGeneticsNodalMarginal2016b] [@zhangGenomicLandscapeMantle2014]
RAF1 2 [@jalladesExomeSequencingIdentifies2017]
RAPGEF2 2
RCOR1 2 [@spinaGeneticsNodalMarginal2016b]
RFTN1 2 [@arthurGenomewideDiscoverySomatic2018; @dunsCharacterizationDLBCLPMBL2021b]
ROCK1 2 [@jalladesExomeSequencingIdentifies2017]
RPL1L 2 [@spinaGeneticsNodalMarginal2016b]
SAMD5 2 [@spinaGeneticsNodalMarginal2016b]
SCG3 2 [@spinaGeneticsNodalMarginal2016b]
STXBP5 2 [@spinaGeneticsNodalMarginal2016b]
SWAP70 2 [@rossiCodingGenomeSplenic2012c]
TAF1 2 [@spinaGeneticsNodalMarginal2016b] [@morinMutationalStructuralAnalysis2013]
TBK1 2 [@jalladesExomeSequencingIdentifies2017]
TCTN2 2 [@spinaGeneticsNodalMarginal2016b]
TNIP2 2 [@vandenbrandRecurrentMutationsGenes2017]
TRRAP 2 [@rossiCodingGenomeSplenic2012c] [@parryWholeExomeSequencing2013]
USH2A 2 [@parryWholeExomeSequencing2013]
WAC 2 [@rossiCodingGenomeSplenic2012c] [@reddyGeneticFunctionalDrivers2017]
WNK1 2 [@jalladesExomeSequencingIdentifies2017] [@thomasGeneticSubgroupsInform2023; @hubschmannMutationalMechanismsShaping2021b]
ZNF9 2 [@spinaGeneticsNodalMarginal2016b]

References

Disclaimer

The content in these pages has been populated, in part, by an automated process. Although we have scrutinized every page to ensure accuracy, errors will inevitably exist. If you find an error please report it as an issue and we will address it.

In particular, let us know if you feel that an important citation is missing or if a paper has been cited incorrectly.

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

You are free to:

Share — copy and redistribute the material in any medium or format for any purpose, even commercially.

Adapt — remix, transform, and build upon the material for any purpose, even commercially. The licensor cannot revoke these freedoms as long as you follow the license terms.

Clone this wiki locally