ZFP36L1
ZFP36L1 is one of a number of genes affected by aberrant somatic hypermutation in B-cell lymphomas, which complicates the interpretation of mutations at this locus.
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timeline
title Publication timing
2011-07-27 : Morin : DLBCL
2015-02-12 : Reichel : PMBL
2017-05-01 : Albuquerque : DLBCL
2018-04-12 : Schmitz : DLBCL
2018-05-01 : Chapuy : DLBCL
2018-10-01 : Arthur : DLBCL
2019-09-26 : Panea : BL
2021-05-05 : Hubschmann : DLBCL
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in MCL not firmly established |
 |
1 | high-confidence PMBL/cHL/GZL gene[@reichelFlowSortingExome2015] |
 |
2 | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@paneaWholeGenomeLandscape2019] |
 |
1 | aSHM target and high-confidence DLBCL gene [@morinFrequentMutationHistonemodifying2011] |
include:DLBCL_ZFP36L1.md include:BL_ZFP36L1.md
| chr_name | hg19_start | hg19_end | region | regulatory_comment |
|---|---|---|---|---|
| chr14 | 69257848 | 69259739 | TSS | active_promoter |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
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