zhangGeneticHeterogeneityDiffuse2013
| Entity | Tier 1 genes | Tier 2 genes | Tier 3 genes |
|---|---|---|---|
| DLBCL | 15 | 10 | 275 |
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This study, New Tier 1, 15
New Tier 1, DLBCL Tier 1, 15
This study, New Tier 2, 10
New Tier 2, DLBCL Tier 2, 10
This study, New Tier 3, 275
New Tier 3, DLBCL Tier 3, 275
All other DLBCL studies, DLBCL Tier 1, 112
All other DLBCL studies, DLBCL Tier 2, 166
All other DLBCL studies, DLBCL Tier 3, 114
| New gene | DLBCL tier | Average variant quality | QC outcome |
|---|---|---|---|
| ARID1A | 1 | ||
| BCL7A | 1 | ||
| DTX1 | 1 | ||
| FBXW7 | 1 | ||
| HIST1H2BK | 1 | ||
| KLHL14 | 1 | ||
| KMT2C | 1 | ||
| MGA | 1 | ||
| MTOR | 1 | ||
| NOTCH2 | 1 | ||
| OSBPL10 | 1 | ||
| RHOA | 1 | ||
| TRRAP | 1 | ||
| ZNF292 | 1 | ||
| ZNF608 | 1 |
| New gene | DLBCL tier | Average variant quality | QC outcome |
|---|---|---|---|
| BTBD3 | 2 | ★ ★ ★ ★ ☆ | PASS |
| INO80 | 2 | ||
| JAK1 | 2 | ||
| JAK3 | 2 | ||
| PIK3R1 | 2 | ||
| SETD2 | 2 | ||
| SMEK1 | 2 | ||
| STAT5B | 2 | ||
| UBR5 | 2 | ||
| ZEB2 | 2 |
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